Now that marijuana or cannabis has become more accepted in the U.S, many people have become curious about the world of medical and recreational marijuana.聽

The most common cannabis extracts are CBD and THC.

While both have their pros and cons, they鈥檙e entirely different.聽

Learn about the similarities and differences between these two popular cannabinoids, which one you should use, and what to watch out for as you shop.聽

What鈥檚 the Difference Between CBD and THC?

Cannabidiol (CBD) and tetrahydrocannabinol (THC) are two different compounds extracted from the cannabis plant.

While many people are aware that they鈥檙e two separate substances, it鈥檚 a bit difficult to tell the differences between these compounds.

One key fact to remember is that both hemp and marijuana are sources of CBD. It means you can obtain CBD oil from either of these plants. However, hemp contains less than 0.3% THC, while marijuana has a much higher THC content.

You will commonly find CBD sold in various forms such as oils, edibles, gummies, and topicals. Marijuana is sold in many forms, available in oils, edibles, tinctures, and capsules, and can be consumed in different ways other than smoking.

Marijuana is in high demand, even in areas where it鈥檚 illegal. This is because THC, its psychoactive constituent, gives the feeling of being 鈥渉igh鈥� when people use it. There are many ways to consume CBD and THC聽

CBD and THC are different compounds, but both affect the body鈥檚 endocannabinoid system (ECS). They have that in common but differ in how they interact with the ECS.

CBD vs. THC Chemical Differences

CBD and THC have pretty similar chemical structures. Both have the same molecular formula 鈥� 30 hydrogen atoms, 21 carbon atoms, and 2 oxygen atoms. Their molecular composition is similar, but their arrangement is a little different.

This difference in the arrangement of elements is why CBD and THC provide different effects on the body鈥檚 endocannabinoid system (ECS).

How the body鈥檚 endocannabinoid receptors react to THC or CBD can affect the brain鈥檚 release of neurotransmitters. These neurotransmitters are the chemicals that act as messengers between cells, managing pain, sleep, immune system functions, mood, memory, and other bodily functions.

CBD vs. THC Legal Differences

In the U.S., both THC and marijuana are considered controlled substances. It means that selling, consuming, and cultivating marijuana is not legal under federal law.

However, the legal status changes when it comes to state laws. There are 33 states (plus Washington DC) that have policies enacted to allow some form of medical or recreational use of marijuana as of July 2020. But the exact details differ in each state.

Some states legalized its medical and recreational use, while others have only legalized medical marijuana. Some states also barred sales for recreational purposes but allowed the growing and possessing of recreational marijuana.

The legal status of CBD and THC is different for every state. CBD derived from hemp is legal in all 50 states, but CBD or THC derived from marijuana are legal in roughly half of the United States.聽

Also, the laws about cannabis and its derivatives change rapidly. You should always check your local state laws before using any product containing THC or CBD.

CBD vs. THC Psychoactive Effects

The psychoactive compound that produces the 鈥渉igh鈥� is THC.聽

CBD is non-intoxicating which means it will not make you feel high.聽

The difference in psychoactivity stems from the fact that THC and CBD affect different receptors in the brain. This causes different effects on the body, with THC producing feelings of being 鈥渉igh鈥� while CBD does not.

To date, scientists have identified two cannabinoid receptors located in different areas of the body. Since they are in various areas of the body, these receptors help regulate different body functions.

A) CB1 Receptors

CB1 receptors are primarily found in the brain but also throughout the entire body. When CB1 receptors are activated via endocannabinoids, it causes a shift in neurotransmitters like serotonin. This is what’s behind the psychoactive effects of CB1 agonists like THC.聽

CBD, on the other hand, doesn鈥檛 bind with CB1. It only helps to activate the receptor by increasing its anandamide levels. CBD can also stop THC from binding with this receptor, which neutralizes THC鈥檚 intoxicating effects.

B) CB2 Receptors

The other receptor is the CB2 receptor, primarily found in cells in the immune system and related structures. CB2 receptors are prominent in the gastrointestinal system and spleen, which affects appetite, immune system functions, and pain management.

THC can bind to both CB1 and CB2 receptors, but CB1 seems to be its main target. But because it binds to both, it also helps relieve pain and improve mood.

CBD, on the other hand, more frequently interacts with CB2 receptors. CBD’s interaction with CB2 receptors promotes anti-inflammatory response in the body, which may also have some benefits for cancer patients.

CBD vs. THC Medical Benefits

People use CBD products for their many potential medical benefits. CBD may help alleviate arthritis pain, diabetes, Crohn鈥檚 disease, multiple sclerosis, and epilepsy. Also, CBD is often used to control chronic pain, insomnia, inflammation, and anxiety.

THC and CBD often have similar effects and are used to treat many of the same conditions. But there are important differences in their use.聽

CBD is most often used therapeutically, relieving symptoms of ailments such as:

• Depression
• Anxiety
• Seizures
• Post-traumatic stress disorder (PTSD)
• Migraines
• Inflammation

On the other hand, THC is the active ingredient in medical marijuana; people use it to alleviate a wide range of health conditions, including:

• Tremors
• Insomnia
• Glaucoma
• Pain from arthritis, fibromyalgia, & migraines
• Chemotherapy-induced nausea
• Poor appetite caused by cancer treatment

The FDA has not approved cannabis yet for treating any conditions. However, it has approved certain drugs that contain THC or CBD.聽

Some of these medications include:

1. Marinol and Syndros contain dronabinol, which is synthetic THC. Marinol and Syndros can treat vomiting and nausea caused by the effects of chemotherapy in treating cancer.
2. Epidiolex contains CBD, which is used to treat seizures related to Lennox-Gastaut and Dravet syndromes, forms of epilepsy.
3. Cesamet contains nabilone, a synthetic substance similar to THC. It is used to treat appetite problems and weight loss caused by HIV/AIDS and chemotherapy.

Benefits of Using CBD & THC Together

Is it safe to use CBD and THC together?聽

Cannabis plants have over 120 different phytocannabinoids that include CBD and THC. They act on the body鈥檚 endocannabinoid system, so your body remains in homeostasis or balance.

THC and CBD are just two of the many phytocannabinoids. You can take them in different forms and a variety of ways, either separately or together.聽

So what happens if you use them together?

Some research suggests that taking them together or with terpenes (organic compounds found in the cannabis plant) increases their effects. This is said to be due to what is called the entourage effect.

According to research, phytocannabinoids and terpenes offer additional medical benefits when taken together. Several studies found they can benefit people suffering from anxiety, pain, inflammation, fungal infection, epilepsy, and cancer.

Another notable effect is the reduced side effects of THC, which include hunger, anxiety, and sedation. Taking CBD with THC is said to help reduce these side effects. However, more research is needed to confirm these claims.

CBD vs. THC Side Effects

CBD is relatively safe even when you take it in large doses. According to research, the side effects of CBD mainly occur due to interactions with other medicines.聽

The common side effects of CBD include:

• Fatigue
• Diarrhea
• Dizziness
• Weight loss
• Appetite changes

THC, on the other hand, has several temporary side effects. These symptoms include:

• Red eyes
• Dry mouth
• Anxiety
• Memory loss
• Increased heart rate
• Slower reaction times
• Coordination problems

The side effects of THC have to do with its psychoactive properties. The good thing is neither CBD nor THC are fatal.聽

But the high use of THC may have some long-term adverse psychiatric effects, especially in adolescents who took large amounts of THC.

Drug Testing For CBD & THC

Drug tests are used to detect the amount of THC in your blood as set forth by guidelines from the Substance Abuse and Mental Health Services (SAMHSA).聽

In other words, drug testing is only concerned with the THC compound present. It鈥檚 this compound that can create problems concerning travel or employment.

It will take a huge dose of CBD to trigger a false-positive result on a drug test if your test is looking for THC content in the blood.聽

Drug test center experts estimate that CBD users would have to invest more than 2,000 mg to produce a “false positive” on their drug test. For a point of reference, the average user of CBD consumes between 120 and 160 mg. daily.

Summary: CBD vs. THC Similarities & Differences

CBD and THC are often confused as being the same thing because of how they look and come from the same plant. But these compounds have many important differences.

While their chemical makeup is similar, each cannabinoid has a different effect on the body. THC is commonly used to manage symptoms associated with insomnia, glaucoma, pain, nausea, and appetite issues. CBD is often taken for relief from anxiety, depression, anxiety, migraines, and inflammation. CBD and THC can be used together to increase their effects on the body and help with anxiety, pain, and inflammation.

THC produces psychoactive effects resulting from its more commonly binding with CB1 receptors in cells. CBD does not produce this “high” as it does not react the same way with the body.

THC is federally illegal, while CBD is legal to use in most states.聽 As a result, drug testing focuses on detecting THC levels in the blood and can cause employment issues. CBD does not pose such a threat for users.

But before taking CBD or THC products, be sure to consult with a medical professional to ensure that these products are safe to use with any other medication you may be taking.

Reference Cited:

1. Atakan, Z. (2012). Cannabis, a complex plant: Different compounds and different effects on individuals. Therapeutic advances in psychopharmacology, 2(6), 241-254 []
2. Ferber, S. G., Namdar, D., Hen-Shoval, D., Eger, G., Koltai, H., Shoval, G., … & Weller, A. (2020). The 鈥渆ntourage effect鈥�: terpenes coupled with cannabinoids for treating mood disorders and anxiety disorders. Current Neuropharmacology, 18(2), 87-96. []
3. National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention. What You Need to Know 口交视频 Marijuana Use in Teens. April 13, 2017.聽 Marijuana and Public Health []

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Do terpenes matter when choosing CBD oil?

More importantly, should you buy CBD oil with terpenes?

The answer to both questions is yes.

Terpenes are important. When added to CBD oil, terpenes improve the taste and enhance the overall effectiveness of the oil.聽

To help you understand terpenes better, this article discusses what terpenes are, their benefits and effects, and their importance in CBD oils.

What are Terpenes?

All types of plants produce terpenes, and according to experts, there are over 20,000 different types of terpenes found in nature.

Trees, shrubberies, grass, flowers, fruits, vegetables, herbs, and even common weeds all have terpenes. They only differ in the types of terpenes they produce and their concentrations within the plant.

Terpenes are the reason why plants have different colors (pigment), aromas, flavors, and even effects.

They also serve as the plant鈥檚 protective system. The aroma and flavor they give off protect the plant against its natural predators like insects and animals. They also help strengthen the plant cells, protecting them against air pollutants and the sun’s UV rays.

These compounds also play an important role in plant reproduction. Their bright colors and sweet aroma, for example, attract pollinators like bees and butterflies. They carry the pollen from one plant to another, which of course, is vital for reproduction.

Terpenes also serve as the plant鈥檚 immune system, helping it fight off disease and illnesses. They have antibacterial, antifungal, antiviral, and other medicinal properties that maintain the plant鈥檚 health.

These properties are also why we benefit greatly from consuming vegetables and fruits.

Does CBD Oil Contain Terpenes?

Do all CBD oils contain terpenes?

Well, it depends on the type of CBD oil.

If you have pure CBD oil (called CBD isolate), it鈥檒l only have CBD. It won’t have any additional compounds like other cannabinoids and terpenes.

On the other hand, using broad-spectrum or full-spectrum CBD oil means you鈥檒l also be getting additional cannabinoids and terpenes. These phytochemicals all work together to produce positive effects on your health.

The only difference between the two is that full-spectrum CBD oil also contains traces of THC 鈥� typically 0.3% or less.

What are the Popular Terpenes Found in CBD Oil?

Cannabis produces over a hundred different types of terpenes, but only a few have been well-studied of these numbers.

Below are some of the best-researched terpenes found in cannabis plants.

1. Limonene

Also found in citrus fruits like orange and lemon, limonene has a refreshing citrusy and spicy aroma that energizes the mind and body.

This terpene helps relieve stress by boosting mood. Limonene also reduces swelling and pain. It also has antibacterial and antifungal effects that control infection.

2. Linalool

An aromatic terpene also found in lavender and rose, linalool produces a rich floral scent with hints of citrus fruits and spices.

Linalool also helps with discomfort. It eases tension, stress, sleeplessness, and forgetfulness. This terpene also fights bacteria and fungi.

3. Caryophyllene

Caryophyllene, also found in hops and cloves, gives off a spicy and woody aroma.

This terpene eases pain and inflammation. Its antibacterial and antifungal properties help fight off infection. Called 鈥�Beta-Caryophyllene,” this caryophyllene helps fight diabetes and its complications. There are

4. Pinene

A refreshing and invigorating terpene, pinene is commonly found in pine needles.

Pinene refreshes the mind, enhances memory, and helps clear brain fog. It also helps control pain and inflammation as well as reduce seizures.

There are two structural isomers of pinene found in nature called the Alpha Pinene and the Beta Pinene.

5. Myrcene

Myrcene has an interesting aroma. It gives off an earthy and musky aroma with robust fruity and herbal notes. This terpene is also found in mango, lemongrass, basil, and hops.

This Myrcene terpene has many therapeutic effects. It not only reduces pain and inflammation but also improves mood and sleep and fights bacteria. Myrcene also relaxes the muscles.

6. Humulene

Also found in black pepper, ginseng, sage, and hops, humulene offers a spicy, earthy, and woody aroma.

Humulene is called the jack of all trades of terpene and relieves discomfort and inflammation. It also has properties that help control weight.

7. Terpinolene

A terpene with floral, herbal, and piney aroma, terpinolene can also be found in apples, ginseng, nutmeg, and flowering plants like lilacs.

Terpinolene fights off infection caused by bacteria and fungus. It also helps improve sleep.

8. Ocimene

Ocimene also found in basil, lavender, and tarragon has an energizing and refreshing aroma. It smells sweet and woody with herbal and floral notes.

This terpene has antibacterial, antiviral, and antifungal effects. Ocimene also has anti-inflammatory as well as antioxidant properties.

9. Bisabolol

Also produced by chamomile and sage, bisabolol has a sweet, floral scent.

Bisabolol helps control pain and inflammation聽as well as fight infection caused by bacteria.

10. Eucalyptol

Minty and refreshing, eucalyptol is also produced by tea trees, rosemary, sagebrush, and peppermint.

Eucalyptol helps with pain and infections caused by fungi and bacteria. It also refreshes the mind and helps enhance memory. Its antioxidant properties also protect many organs from diseases.

Some terpenes like limonene, linalool, pinene, myrcene, terpinolene, and humulene also have anti-cancer effects.

What are the Benefits and Effects of Terpenes in CBD Oil?

Terpenes make up part of the entourage effect associated with cannabis.

The entourage effect is a phenomenon that states that all the compounds in cannabis work together in producing stronger beneficial effects compared to isolates.

Of the different CBD forms, this effect is strongest in full-spectrum CBD oil. Its cannabinoids (including THC) and terpenes amplify each other鈥檚 health effects.

Their presence makes the CBD oil more potent and more effective in maintaining mind and body health.

Terpenes also add more aroma and flavor to the CBD oil, although their scent and flavor are not as perceptible in CBD oils compared to smoking CBD flowers.

How to Use CBD Terpenes?

How to use CBD products containing terpenes depends on the CBD form, of course.

CBD oils and tinctures are oftentimes used as a sublingual product and placed under the tongue. They may also be added to foods and drinks and ingested like CBD edibles (candies, gummies, brownies, capsules, etc.)

Topicals like balms and ointments produce localized effects and are applied to the skin. CBD cream products like this work best for skin problems as well as joint and muscle aches and pains.

Inhalable CBD products like flowers and vapes are smoked and vaped.

Why Add Terpenes into CBD Oil?

When you smoke CBD-rich flowers, you’re also taking in all its naturally occurring cannabinoids and terpenes.

This isn鈥檛 the case with CBD oils.

We lose some of the plant material鈥檚 cannabinoids and terpenes during the extraction process, affecting the product鈥檚 potency and quality.

Some producers add terpenes back into the product to enhance CBD’s effects to increase its potency and efficacy.

However, the more processed the oil, the less it captures the plant’s essence, and the farther its quality gets from the original source.

When choosing CBD oils with terpenes, the extraction process should matter a lot.

How to Choose CBD Oils & Vapes with Terpenes

Not all CBD oils and vapes are created equal, so you have to be discerning in choosing your CBD product as a consumer.

Below are some tips to choose the best CBD oils and CBD vapes with terpenes.

1. Know the Extraction Process

There are many ways to extract CBD. The most common ones include oil, alcohol, and supercritical carbon dioxide extraction methods.

The supercritical CO2 extraction method produces the cleanest, safest, and most potent end product of these different methods.聽

It doesn’t use too high temperatures that can damage or destroy the cannabinoids and terpenes. This preserves their quality and potency.

Because it鈥檚 solvent-free, the end product doesn’t contain residual solvents. Toxic residues and byproducts are commonly seen in the alcohol extraction method.

Moreover, this method also kills off any pathogenic microorganisms (bacteria, fungi, etc.), resulting in a safe, contaminant-free product.

2. Look for Certificate of Analysis or COA

It would help if you also looked for the CBD product鈥檚 certificate of analysis done by a reputable laboratory testing facility. This proves that the product underwent necessary testing to check for its safety, quality, and potency.

The COA should show the product is contaminant-free and contains the stated cannabinoid and terpene profile and potency.

3. Read Product Reviews

Reading product reviews and customer feedback is just as important.

Don鈥檛 buy CBD products that receive more negative than positive reviews. If most of those who tried the product didn鈥檛 enjoy it, you probably won’t either.

Product reviews give you an idea of just how good and effective (or not!) the CBD with terpenes is.

4. Choose Full-Spectrum CBD

If you’re after a more potent effect, choose full-spectrum CBD oils and vapes. The presence of more cannabinoids (including THC) and terpenes helps add to the product鈥檚 overall potency and effectiveness.

Again, look for the product鈥檚 COA. Make sure that it shows not only the cannabinoid profile but also its terpene profile. Check their concentration as well.

Final Thoughts 鈥� Terpenes in CBD Oil Matter

Terpenes, on their own, have many therapeutic effects.

They help relieve pain and swelling, boost mood, fight infection, improve sleep, and relax muscles. Some terpenes enhance memory, and some may even reduce the proliferation of cancer cells.

Does their presence in CBD oil matter?

It definitely does!

Terpenes add to the overall aroma and flavor of CBD oil. More importantly, they enhance CBD’s beneficial effects.

Do you pay attention to terpenes in your CBD oil? What blends of aromas work best for you? Let us know in the comments below!

References Used In This Article

1. d’Alessio, P. A., Bisson, J. F., & B茅n茅, M. C. (2014). Anti-stress effects of d-limonene and its metabolite perillyl alcohol. Rejuvenation Research, 17(2), 145鈥�149. []
2. Hashiesh, H. M., Meeran, M., Sharma, C., Sadek, B., Kaabi, J. A., & Ojha, S. K. (2020). Therapeutic Potential of 尾-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications. Nutrients, 12(10), 2963. []
3. Salehi, B., Upadhyay, S., Erdogan Orhan, I., Kumar Jugran, A., L D Jayaweera, S., A Dias, D., Sharopov, F., Taheri, Y., Martins, N., Baghalpour, N., Cho, W. C., & Sharifi-Rad, J. (2019). Therapeutic Potential of 伪- and 尾-Pinene: A Miracle Gift of Nature. Biomolecules, 9(11), 738. []
4. Valente, J., Zuzarte, M., Gon莽alves, M. J., Lopes, M. C., Cavaleiro, C., Salgueiro, L., & Cruz, M. T. (2013). Antifungal, antioxidant, and anti-inflammatory activities of Oenanthe crocata L. essential oil. Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association, 62, 349鈥�354. []
5. Seol, G. H., & Kim, K. Y. (2016). Eucalyptol and Its Role in Chronic Diseases. Advances in experimental medicine and biology, 929, 389鈥�398. []

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It鈥檚 understandable how using CBD for the first time can confuse people. CBD, after all, remains unregulated.

What鈥檚 the right dose to use? Should I take it in the morning or at night?

To help you with your CBD journey, this guide teaches you how to find the optimal CBD dosage and what time of the day to take it.聽

What Time Should You Take CBD Oil?

Now, let鈥檚 find the best time to take CBD oil.

Similar to finding your best dose, many factors to consider when determining your CBD schedule. These include:

• The reason why you’re taking CBD in the first place
• Your expectations and desired effects
• The CBD product or form
• Frequency of taking CBD oil

Effects of CBD Oil in the Morning

When you take CBD oil in the morning, it not only boosts your energy but also relieves some of your discomforts.

Because you鈥檇 be feeling more energized and in a healthier mood, there鈥檒l also be a boost in your motivation and an increase in your productivity.

The increase in energy may also help you enjoy your exercise regimen more.

Effects of CBD Oil at Night

Taking CBD oil at night helps relax the mind and the body. Your discomfort eases, and your mind feels calmer and more peaceful.

With your stress and discomfort gone, it鈥檒l be much easier to fall into a long, restful sleep. You’ll also feel more energized in the morning since your sleep quality improved.

Best Time to Take CBD by Product Type

Now that you know the most effective time to take CBD, choosing the best CBD form or product is the next step.

A) Oral CBD (Sublingual & Ingestible)

Sublingual CBD oils and tinctures are usually placed under the tongue, while ingestible CBD-like capsules and edibles are swallowed whole.

Sublingual CBD offers a faster onset of effects since CBD is quickly absorbed by the cells in the mouth. You’ll feel the effects in less than 30 minutes.

On the other hand, Ingestible CBD takes some time since it has to go through several organs like the stomach and the liver first. You’ll feel the effects anywhere from 30 minutes to about two hours, depending on your metabolism.

Sublingual CBD is best for acute symptoms and may be used on an as-needed basis. Its fast onset of effects can immediately give you some relief, with the effects lasting for about two to four hours.

On the other hand, Ingestible CBD is best for chronic symptoms since CBD stays longer in the system. It has more time to activate more endocannabinoid systems and produce its health effects. The effects typically last about six to eight hours, so it鈥檚 best to use ingestible CBD like you would any other supplement 鈥� regularly and preferably at the same time of the day.

B) Inhalable CBD (CBD Flowers and Vape)

CBD flowers are usually smoked, while CBD vapes are inhaled using vaporizers.

Like sublingual CBD, both produce a fast onset of effects since CBD is immediately absorbed and directly goes into the bloodstream. This type of CBD product works best for acute symptoms and may also be used as needed.

The effects of inhalable CBD usually last about two to four hours as well.

Of the two, though, CBD vapes are safer and healthier to use. It doesn’t produce harmful, carcinogenic byproducts, which occur during the combustion of paper and dried flowers.

C) CBD Topicals

CBD topicals include ointments, balms, creams, salves, lotions, gels, among others.

Unlike the first two forms of CBD, which may produce widespread effects, CBD applied topically only produce localized effects. The cannabinoid doesn’t enter the bloodstream. Instead, it activates the endocannabinoid systems found in the skin cells.

CBD topicals are perfect for muscle as well as joint aches and pains. This may also be good for skin conditions like acne, hives, or insect bites.

It may take about 30 minutes to an hour before you feel the effects, so to increase absorption, be sure to wash the area with soap and clean water. This removes the dirt and grime that can slow down the rate of absorption.

The effects of CBD topicals usually last about five hours. It may be taken on a regular or an as-needed basis.

How Often Can You Take CBD Oil?

Some people take CBD oil once a day, while some take it twice or thrice a day.

Again, this depends on your preferences, so listen to your body as you find the best CBD dose.

For example, you’re using CBD for health and wellness maintenance only. Then you may want to start with low-strength CBD and take it once a day. For an energy boost, take it in the morning. To have a more relaxing sleep, then take it at night.

However, if you’re using CBD to help manage some of your health concerns, then you may want to start with medium- to high-strength CBD. You may use the CBD dosage calculator discussed above to get the best dosage for your body weight and symptoms.

You can experiment and take the whole dose once a day or divide the dose into two and take a half in the morning and a half at night.

Stay on one routine for a few days, and if it doesn’t work, then switch to the next. If it still didn鈥檛 work, then you might need to increase your CBD dose.

If you need more help with CBD use, we recommend seeing your doctor. He can help you come up with a good CBD schedule.

Reasons for Taking CBD Oil

CBD acts on the endocannabinoid system, the main function of which is to help maintain balance and homeostasis within your mind and body. CBD also influences other receptors responsible for maintaining this balance.

Simply put, CBD will help you where and when you need it most. It will stimulate these biological systems, helping them promote and maintain balance.

To take full advantage of CBD鈥檚 health effects, know why you need it in the first place.

Is it because you need an energy boost to start the day? Or maybe you need a mood booster? How about some control over your aches and pains to get through your daily tasks?

If so, then take your CBD oil in the morning. This way, CBD helps you prepare and feel ready to face the day.

Do you need help in winding down and relaxing, or maybe you need a little push to help you sleep better?

If this is your reason, then take CBD oil at night. It helps you relax and unwind as you settle down for the night.

What鈥檚 The Dose of CBD?聽

People respond differently to CBD. The dose that works for one may not necessarily work for you.

Remember, many factors influence your CBD dose. These include:

• Metabolism
• Weight
• Size
• Medical condition
• Symptoms
• Other medications or drugs you’re taking
• CBD potency
• Type of CBD product
• How well you tolerate CBD

Now, the general rule for CBD dosing is to take:

• 1 mg of CBD per 10 lbs of body weight for low-strength CBD
• 3 mg of CBD per 10 lbs of body weight for medium-strength CBD
• 6 mg of CBD per 10 lbs of body weight for high-strength CBD

Let’s say, for example, you weigh 150 pounds, then you’ll need 15 mg of CBD for mild symptoms, 45 mg for moderate symptoms, and 90 mg for severe symptoms.

Next, determine the milligrams of CBD per mL or one full dropper.

To calculate how much CBD is in an mL, divide the total CBD milligrams by the bottle size in mL.

Let鈥檚 say you have 900 mg CBD in a 30 mL bottle, then divide 900 by 30, giving you 30 mg of CBD per 1 mL or one full dropper. One full dropper has about 20 drops.

Since you鈥檒l only need 15 mg of CBD for mild symptoms, for example, then use half a dropper or about 10 drops.

Start Low & Go Slow

You may want to start with a lower dose than what you initially calculated to avoid side effects. Stay on that dose for about three to five days, so your body gets used to CBD.

If there鈥檚 no improvement, then gradually increase the dose.

If there are some side effects, then decrease the dose.

Finding the right CBD dose is a trial and error experience before you find your sweet spot, so be patient.

Final Thoughts 鈥� Best Times to Take CBD Oil

When鈥檚 the best time of the day to take CBD oil?

Well, there鈥檚 really no right answer to this.

When using CBD oil for the first time, listening to your body鈥檚 reaction to CBD is important. How your body responds to CBD can help you determine your CBD schedule.

Take notes of the effects based on the doses, frequency of use, the time you took CBD oil, etc., and then adjust accordingly.

Always remember that 鈥渙ne-size-fits-all鈥� doesn’t apply to CBD use. If you want to find the best dose, then you have to be patient and consistent.

Finding the best dose and frequency of use won’t be easy, but with patience and consistency, you’ll soon develop a CBD schedule that works for you.

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Ever since cannabis products started becoming available, products offering CBD, THC, or both have become available in a growing range of varieties.

In the past, the most common products were CBD oils and raw hemp flowers.

Now, you can find CBD in just about any form imaginable. One of the rising stars in the industry is CBD rosin (sometimes called CBD concrete) 鈥� which is a special type of CBD extract.

But what is CBD rosin, exactly?

Let鈥檚 take a closer look at what it is, and how to make CBD rosin at home.

What Is CBD Rosin?

Essentially, CBD rosin is similar to other cannabis or hemp concentrates, the main difference being that while many concentrates are made using harsh solvents (which can leave nasty chemical residues). Rosin is extracted using pressure and heat but no solvents at all, resulting in greater potency and purity.

CBD rosin is highly versatile. Perhaps the most common involves 鈥渄abbing鈥� (a process that involves vaporizing your resin through a 鈥渄ab rig鈥� attached to a water pipe, which many people prefer because it is one of the fastest, most powerful delivery methods).

You can also smoke CBD rosin in a pipe, roll it into or apply it to the outside of a joint, or use it in creating CBD oils, tinctures, edibles, topical creams, or virtually any other product.

The Benefits of Using CBD Rosin

Now, among the many CBD product types on the market, what are the benefits of using rosin?

Besides its extreme versatility, many CBD users choose rosin because it鈥檚 a particularly health-conscious option. While CBD products are often extracted using hydrocarbons such as butane or propane, rosin is entirely free of chemical solvents during extraction.

In addition to CBD, this method also retains a range of compounds such as terpenes, CBC, CBG, CBN, and various fatty acids, all of which deliver a range of health benefits.

What鈥檚 more, solvent-free CBD rosin tends to have a better taste than other extraction processes.

How to Make CBD Rosin?

Next up 鈥� how to make CBD rosin.

You might think that it takes a lot of fancy equipment and master鈥檚 degree-level know-how to make rosin. But you鈥檇 be wrong. In truth, all you really need is a mechanical press, CBD-rich cannabis flower (or any other cannabis/hemp material such as stems, leaves, shake trim, etc.), and some parchment paper.

Let鈥檚 start by taking a look at the press. In theory, you can use any food-grade mechanical press, just like those used for squeezing oil from olives. But there are also presses on the market that is specifically made for cannabis products, and these can be helpful to ensure the best possible combination of pressure and temperature.

If you鈥檙e working under a budget, a simple countertop oil press will get the job done. The benefit to these is that they鈥檙e inexpensive, easy to use, and take up very little space.

If you really want to get serious about making your own CBD rosin, your best bet is to get a press that鈥檚 designed for cannabis products.

PurePressure, for example, is a reputable company that offers a wide range of both manual and automatic presses, as well as a variety of other helpful pressing tools.

Choosing Hemp Flower for Making CBD Rosin

The next essential element is, of course, the cannabis or hemp from which your rosin will be pressed.

While you鈥檒l get the most rosin from the buds or 鈥渇lower鈥� of the plants, you can actually use any part of it 鈥� stems, trim, shake, kief, and so on 鈥� in the pressing process. So feel free to pack it all in: waste not, want not.

Unless you want your rosin to have psychoactive effects, you鈥檙e going to need to specifically seek out cannabis strains that are high in CBD but almost entirely free of THC.

A few popular strains that are packed with CBD but have less than 0.3% THC include:

• Charlotte鈥檚 Web
• Harle-Tsu
• Suzy Q
• Ringo鈥檚 Gift
• ACDC
• Remedy
• Harlequin
• Sour Space Candy
• Cherry Wine

If all else fails, contact your nearest dispensary, and they鈥檒l point you toward the right plant.

Keep in mind that the dryness of your plant matters. Your goal should be to find plant material that is as fresh as possible, which will not only result in greater retention of healthy compounds but often tastes better too. The drier flower will also reabsorb some of your rosins, resulting in a lower yield.

What is the Best Temp to Heat CBD Rich Rosin?

Before we dive into the actual process, a quick word on heat.

Heat is a key part of the rosin pressing process, but it鈥檚 essential that you keep the temperature without a specific range.

Too cool, and you鈥檒l limit your yield.

Too hot, and you鈥檒l burn off all the healthy CBD and other compounds.

So what is the best temp to heat CBD-rich rosin presses?

Your goal should be to maintain a temperature between 160 and 220 degrees for somewhere between 45 seconds and five minutes. Finding a specific temp and time depends on factors like which strain and press you鈥檙e using, as well as your personal taste and potency preferences.

You can raise the temperature as high as 330 degrees, which will result in greater yield but less potency. So if you鈥檙e looking for a larger quantity of more subtle rosin, this is the way to go.

Start out by creating small batches of rosin, and try out different temperatures and times to determine the best ratio. Keep track of factors like temperature, time, strain, and plant material weight so that you can not only track results and adjust as necessary but so that once you do find your preferred recipe, you can replicate it with ease.

How to Make CBD Rosin at Home?

Now without further ado, on to the actual process for making CBD rosin:

Step 1: Prep the Material

Prepare your plant material by breaking it up into small pieces. Make sure there鈥檚 a somewhat uniform ratio of flowers to stems to trim between batches to ensure consistency. Feel free to play around with the levels, and document any adjustments.

Step 2: Back The Material Into a Mesh Bag

If your press came with a mesh bag, pack it with the plant material, then place this on a piece of parchment paper. If you don鈥檛 have a bag, no worries, just place the plant material directly onto the parchment paper. The only downside to this is that you may end up with some plant material leftover in your rosin.

Step 3: Set the Temperature

Use the manual to set the temperature and pressure on your press correctly, then allow it to heat. Place the bag or parchment paper between the pressing plates.

Step 4: Start Applying Pressure

If you鈥檙e using a manual press, crank it down to the desired pressure. If it鈥檚 automatic, simply set it to press. Some automatic presses have built-in timers; otherwise, relieve the pressure after the desired amount of time.

Step 5: Remove The Bag

If you鈥檙e using a mesh bag, remove the bag and set it aside. The rosin should be left behind in a thin, semi-translucent, sappy layer. Now scrape the rosin from the paper using the tool included with your press, a paint scraper, a knife, or anything else that will get the job done.

Step 6: Storing Your Rosin

Ideally, you鈥檒l store your rosin in a glass container. This makes it easier to handle than when stored in plastic (to which it tends to stick), and it ensures that no potentially harmful plastic byproducts will leach into your rosin. If you鈥檒l be bringing your rosin on the go and you鈥檙e worried about breaking a glass container, silicone is a good alternative.

If you only plan on storing your rosin for a few weeks, it should be pretty stable, so you won鈥檛 have to worry about losing potency. But if you鈥檒l be storing long-term, be sure that it鈥檚 kept in an airtight container someplace cool and dark.

Final Thoughts on CBD Rosin

There you have it 鈥� your very own homemade CBD rosin. It鈥檚 perfect for smoking or making edibles, and properly stored will hold its potency for months or even years.

At this point, CBD is legal in most states and countries, but there are still a few that have resisted the CBD call to health. Be sure to check your local regulations.

Do you have any questions about how to make CBD rosin or CBD rosin in general? Comment below to learn more.

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In recent years, several studies have indicated the potential health聽benefits of using CBD. As a result, scores of patients have begun looking to CBD as a safe and natural alternative to traditional pharmaceutical drugs like Xanax.

Perhaps the most commonly sought benefit of CBD involves its ability to help reduce and regulate anxiety, stress, depression, and other mood issues.

You might be wondering, what鈥檚 the deal with CBD and Xanax interactions? And can CBD oil help with benzo withdrawal?

Let鈥檚 take a look.

Can CBD Help With Anxiety?

Anxiety-related disorders are the most common mental health disorders in the United States, with as many as suffering from it at some point in their lifetime.

As a result, takes some form of psychiatric drug to treat their condition.

Patients taking these drugs 鈥� among which Xanax is one of the most common 鈥� end up dealing with negative side effects such as memory problems, dizziness, drowsiness, blurred speech or vision, irritability, trouble concentrating, nausea, weight changes, headaches, upset stomach, loss of libido, and a host of other issues.

Luckily, research has shown that for many patients, CBD might be the safer, natural solution they鈥檙e looking for.

that CBD may help treat a slew of anxiety disorders such as:

• Generalized Anxiety Disorder
• Panic Disorder
• Post-Traumatic Stress Disorder
• Social Anxiety Disorder
• Obsessive-Compulsive Disorder
• And more

CBD accomplishes this by interacting with receptors in your body鈥檚 endocannabinoid system, which is the system that regulates behaviors relating to fear and anxiety. The science behind how CBD interacts with these receptors is extremely complicated.

While more study is needed to verify whether or not CBD in itself is a solution to anxiety, the findings so far are promising. That doesn鈥檛 mean, however, that you should quit your current medications cold turkey in favor of CBD. From what we know now, the effects of CBD are rather subtle.

CBD does seem to be an excellent supportive treatment for mild to moderate symptoms.

CBD and Xanax Interaction

The most important thing you should know about CBD and Xanax interactions is that in some cases, the combination may increase certain side effects of Xanax, such as drowsiness or sedation.

Furthermore, while scientific information about CBD and Xanax interactions is limited, we do have some information on how Xanax interacts with cannabis in general. When the two are combined, it may boost side effects like confusion and difficulty concentrating.

How to Avoid CBD & Xanax Interaction

The best way to avoid this interaction is to avoid taking both at the same time.

If you still decide to mix Xanax and CBD, it鈥檚 wise to start with a very low dose of CBD and build up gradually over time. Start with a dose much lower than you think you need, and increase the dose each day at a rate of 2 mg of CBD.

This is the best way to avoid serious side effects.

While you鈥檙e increasing the dose, if you notice any side effects, simply reduce the dose again to the day before when there were no side-effects.

It鈥檚 also important to tell your doctor about your plans to use CBD before starting.

How Can CBD Oil Help with Benzo Withdrawal?

In one, it was found that CBD can be a powerful tool for combatting a wide range of addictive behaviors relating to opioid, cocaine, tobacco, and psychostimulant addiction.

When it comes to Xanax (and other benzodiazepines), CBD helps by alleviating the most common side-effects of withdrawal 鈥� such as insomnia, anxiety, and agitation. These symptoms can be severe and are often enough to prevent someone from quitting the drugs altogether.

Don鈥檛 expect CBD to remove these symptoms completely 鈥斅爄t will merely take the edge off to help you get through the worst of it. Know that after a few weeks, you will no longer feel the uncomfortable withdrawal symptoms.

How to Wean Off Benzodiazepines with CBD

Weaning off benzodiazepines should never be done without first consulting with a doctor. After the first 2-weeks of using these drugs, the body will have developed some degree of tolerance.

It can be dangerous to quit benzos after using them for long periods of time. Severe benzo dependence should always be done under direct medical supervision. Serious side effects have been known to occur.

With that said, if you鈥檙e on a low-dose benzodiazepine schedule, or have not been using them for very long. Your doctor may give you the go-ahead to use CBD to help wean yourself off.

Step 1. Consult Your Doctor

It鈥檚 essential that you speak with your doctor before making any major decisions regarding medication changes. Certain drugs, including Xanax, should be weaned off carefully and with proper medical guidance. It can be dangerous to quit Xanax cold-turkey.

Be sure to ask how CBD will interact with all your current medications, and to discuss what will result from reducing or eliminating your Xanax usage.

Step 2. Choose a Quality CBD Product

There is an extremely wide range of CBD products on the market that fall on a spectrum in terms of quality. Low-quality products might not only be ineffective, but they can contain impurities and toxins that could potentially be harmful to your health.

Quality CBD producers extract their CBD from quality hemp, meaning that it鈥檚 been grown organically and is free from pesticides, non-organic fertilizers, and other toxins. They use a CO2 extraction process, which avoids burning off CBD content and other healthy compounds and doesn鈥檛 leave behind chemical impurities. Finally, once their production process is complete, they have their products third-party lab tested to ensure potency and purity and will make these lab findings accessible to customers.

Step 3. Start Low & Go Slow

It鈥檚 best to avoid quitting a substance like Xanax cold turkey. Instead, taper off your usage while gradually introducing higher and higher quantities of CBD to your system.

It may be useful to keep a journal detailing the different effects you experience at different doses. If you begin to notice adverse effects like fatigue, sedation, or dizziness. If this happens, it may be necessary to lower your dose.

Step 4: Settle on a Balance That Works For You

Ideally, you鈥檒l at some point reach a place where Xanax is no longer necessary, and you鈥檙e using CBD alone to treat your anxiety. But the fact is that different people have different bodies, and therefore the ratio of CBD-to-Xanax that鈥檚 right for you might be specific to your circumstance.

Maybe that means no Xanax at all. Perhaps it means only using it occasionally in emergencies. Or perhaps it means maintaining an ongoing but a reduced rate of Xanax while supplementing with CBD.

Final Thoughts: CBD & Xanax

To summarize, CBD has the potential to be a powerful tool for reducing or eliminating the need for pharmaceuticals like Xanax and other benzodiazepines. Take in conjunction the two may result in negative side effects 鈥� so keep that in mind when choosing whether or not CBD is right for you.

From there, it鈥檚 a matter of consulting your doctor, finding the right CBD dosage for your body, and weaning yourself off the benzos slowly.

One of the most exciting aspects of CBD is its potential to help people suffering from pharmaceutical dependence find a natural, safe way to treat anxiety, depression, and other conditions. If you鈥檙e interested in trying CBD, check out one of the quality producers we鈥檝e listed above.

Have any questions about CBD and Xanax interactions, or about how to wean yourself off benzodiazepines with CBD? Comment below to find answers.

References Cited In This Article

1. Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of general psychiatry, 62(6), 593-602.
2. Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics, 12(4), 825-836.
3. Prud’homme, M., Cata, R., & Jutras-Aswad, D. (2015). Cannabidiol as an intervention for addictive behaviors: a systematic review of the evidence. Substance abuse: research and treatment, 9, SART-S25081.

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CBD oils have become increasingly popular over the years. You can find them in several big-box retailers, corner stores, dispensaries, and health food shops across the United States.

The best deals for CBD oils are online when you order directly from the manufacturer.

So how much does a bottle of CBD oil actually cost? How do I know if I鈥檓 paying too much?

In this article, we鈥檒l break all of this down in more detail.

How Much Does CBD Oil Cost?

The price of CBD oils can range between $0.05 to $0.30 for every milligram of CBD. An ounce (standard US bottle size) of oil can cost you $35 to $300.

The average bottle of CBD oil costs around 11 cents for every milligram of CBD. At a standard 20 mg, this works out to around $2.20 per dose.

The more CBD oil you buy, the cheaper it becomes. If you order in bulk, the cost can be as low as 7 cents per milligram, which brings the cost of an average dose down to just $1.40.

Factors That Affect the Cost of a CBD Oil

CBD oils come with different price tags depending upon the plants’ cultivation to extract and prepare the CBD oils.

It also depends on the quality, purity, concentration, spectrum of cannabinoids, techniques, and processes used to prepare and manufacture the oils.

1. Where was the Hemp Sourced?

The best CBD oil comes from organic hemp farms right here in the United States.

Healthy and contaminant-free strains are the best kinds. The origin matters a great deal as this depends on the organic nature, purity, and potency of the oils. The US’s top manufacturing companies either grow the plants on their own land or source them from other farms.

For example, some hemp plants grown in China or India have been shown to contain heavy metals hazardous to the consumer’s health.

On the other hand, the US manufacturers’ organic CBD oils go through stringent testing in compliance with the authorities’ regulations and standards.

With the passing of the farm bill in the United States, it is now legal to grow hemp following the authorities’ standards. The sourcing of natural and organically grown hemp is more expensive than the others in the market.

2. In-House CBD Oil vs. White Labelling

Some manufacturers grow the cannabis and hemp plants on their own fields, extract and produce the CBD oils in-house. Others resort to sourcing the ingredients for larger manufacturers to prepare the products for them.

This is known as 鈥渨hite labeling.鈥� The end product CBD oils are then marketed and shipped to customers. It can cost up to $25,000 to $30,000 to launch, and between $15 and $100 per bottle of oil.

3. Full-Spectrum vs. CBD Isolate Oils

Generally, most manufacturers retain the full-spectrum extract 鈥� these are rich in terpenes and various other plant compounds (including some THC). Preserving the original contents of the strains takes a lot of time, labor, effort, and the use of the right techniques and technology.

4. The Potency of the Oil

The potency is of prime importance when it comes to CBD oils.

Before you go scrambling to purchase those products with lower CBD potency in the hopes that it would save some cash, think again, you鈥檒l actually end up spending more.

Here鈥檚 why.

When low potency CBD oils are used, it won鈥檛 be as effective as the higher potent ones. You will end up having to buy more products to recover and obtain the desired outcome. What makes the potent CBD oils special is that they last longer, and you only need a small amount with each dose.

Curious about how CBD potency is determined?

The potency of CBD is determined by checking the presence of the cannabinoid content along with tetrahydrocannabinol, phytocannabinoids, cannabigerol, cannabidiol, and tetrahydrocannabivarin. Generally, the potency tests are carried out using UV detectors for the chromatography process that studies the mass traces of the cannabinoids.

These tests tell us how much CBD is in the bottle. From here, you can find the potency by dividing the total CBD content by the volume of the bottle.

For example, a 1000 mg CBD oil with 30 mL of oil has a potency of around 33 mg/mL.

5. Presence Of Premium Ingredients In The CBD Oils

CBD oil extracts from the best hemp companies contain other ingredients to help guide the effects of CBD.

The inclusion of additional ingredients or other natural flavorings in the CBD oils boosts the taste, consistency, and health benefits 鈥� but it also makes the product more expensive.

You can expect to find coconut oil, MCT oil, olive, almond oils, or raw hemp seed oils in the products.

6. Third-Party Lab Testing

CBD oil extracts and all the hemp products in the United States should be sent to a third-party lab for testing. This guarantees the purity, potency, and reliability of the CBD oil you鈥檙e using. It doesn鈥檛 matter if you get them on e-commerce websites or at the store, always check if the products are thoroughly tested for potency, purity, and to check for any potential contamination.

Some manufacturers and producers have their own laboratories with state of the art testing facilities and equipment.

However, setting up the testing laboratory with the necessary equipment can be quite expensive. In contrast, other manufacturers have to send it to the third-party labs to test the CBD oils and other related products they prepare. Detailed and in-depth testing of the products is costly, ultimately leading to higher price tags for the end product.

The CBD oils’ laboratory testing cannot be skipped as it ensures clean and pure extracts, quality, potency, safety, and transparency in the manufacturing process.

Key Takeaways: Is CBD Oil Worth The Money?

CBD oils are a popular remedy for a variety of health conditions. Many people prefer to use this natural supplement instead of over the counter medications.

On average, a single milligram of CBD oil costs 11 cents, and the normal recommended dose for adults is about 20 mg. This will cost you roughly about $2.50 for each dose, making it a lot cheaper than purchasing meds from a pharmaceutical with price tags of up to several dollars per tablet.

This is just an estimate 鈥� the cost of CBD oils can vary a lot depending on the quality of the hemp, the potency of the oil, and the inclusion of other premium ingredients or extracts.

When shopping for CBD, it helps to calculate the cost per mg of the oil you鈥檙e looking at and consider the company’s reputation, the potency of the oil, and other factors mentioned above to ensure you鈥檙e getting the best deal possible.

The post How Much Does CBD Oil Cost? 6 Factors That Affect Hemp Prices appeared first on 口交视频.

Although cannabis has gotten a bad reputation as a 鈥渄rug of abuse鈥� due to massive misinformation campaigns in the past, our perception of the plant is changing significantly as more research is done.

It actually appears that cannabis compounds, such as CBD聽and THC, can actually help manage addictive behaviors, and cannabis itself can be considered an 鈥渆xit drug鈥� instead of a 鈥済ateway drug.鈥� (1)

There is evidence that pharmaceuticals that target CB2 receptors may be used in treating cocaine and heroin addiction (2). Certain observational studies have also shown that cannabis may be a safe substitute for substances like alcohol or nicotine (3).

But can you effectively replace CBD with nicotine? How does CBD help people who decide to go cold turkey?

Let鈥檚 dig it up!

Nicotine in Numbers

The World Health Organization (WHO) reports that on top of nicotine, tobacco smoke contains at least 69 substances that are known to cause cancer (4).

The use of tobacco continues to be the leading preventable cause of death in the world, killing roughly 6 million people each year and leading to massive economic losses estimated at more than half a trillion dollars (5).

According to the latest report of the Global Tobacco Surveillance System, which collects data from 22 countries that represent nearly 60% of the world鈥檚 population, there are 1,300 million nicotine users in those countries. 205 million of those users had tried to quit smoking in the past 12 months (6).

Only 4鈥�7% of people are capable of kicking their habit without medicines or other help, while 25% of nicotine users use medication to manage their withdrawal symptoms (7).

Is Nicotine Addiction a Real Thing? Or Is It Just a Bad Habit?

At least two studies have found that 80% of people who have been addicted to certain substances recover from their addiction throughout their lives (8).

Surprisingly, tobacco addiction has the lowest cessation rates.

Is addiction to nicotine actually that strong? Or is there more to it than just a pharmacological effect that shackles the brain?

Although the problem of nicotine addiction is usually attributed to a disorder of the brain caused by a pharmacological substance, it is the habit that paves the way for all addictive behaviors.

When people establish this habit, they focus on the behaviors involved in seeking and consuming the substance rather than the substance itself.

As it turns out, the habit of inhaling smoke or vapor, or the fact that you regularly hold a cigarette in your hand, can be more powerful than the actual nicotine addiction.

In specific cases of nicotine, it鈥檚 very difficult to train animal models to get hooked on the substance. And what鈥檚 more interesting, the rates of nicotine cessation by pharmacological means 鈥� patches, pills, and gums 鈥� is distressingly low.

Can You Replace Nicotine with CBD?

CBD interacts with the human endocannabinoid system (ECS), which is a neurochemical network responsible for controlling the physiological and psychological functions of the body.

Addictive behaviors are one of such functions.

The way CBD acts on the endocannabinoid system is yet to be fully understood, but according to a recent review on the possible role of CBD in treating addiction, 鈥淐BD has been associated with many neural circuits involved in the acquisition of addiction and subsequent drug-seeking behaviors, making it an interesting pharmacological candidate to treat substance-use disorders.鈥� (9)

But are there any studies to back up this interesting theory?

Research on CBD and Nicotine

Only one study has investigated the impact of CBD on nicotine addiction and tobacco smoking.

A has analyzed the effectiveness of CBD against a placebo in the treatment of tobacco addiction. It was a double-blind, randomized, and placebo-controlled study with 24 subjects who smoked more than 10 cigarettes per day.

12 subjects received an inhaler with CBD and the other twelve got an inhaler containing a placebo. The treatment lasted for one week; throughout this time, the research team recorded the subjects鈥� cravings for nicotine and anxiety levels on a daily basis.

In a follow-up interview that was conducted 21 days after the treatment, cigarette consumption in the CBD group had decreased by 40%. The figure stood in stark contrast with the placebo group. Both groups reported the same drop in anxiety and cravings over the treatment鈥檚 duration.

By day 21, the subject returned to the initial condition. The authors of the study indicated the need for larger-scale studies, with longer follow-up to gauge the implications of these pilot findings (10).

How Does CBD Help with Nicotine Addiction?

As mentioned, the exact mechanism behind the effects of CBD on nicotine addiction is not yet fully understood. However, the authors of the above study have a series of explanations, based on the interactions of CBD with the ECS.

One option includes the action of CBD on CB1 receptors 鈥� as a weak reverse agonist 鈥� and its ability to block the enzyme that breaks down anandamide (FAAH), an endocannabinoid (produced in the body) that plays an important role in mood regulation, sensations of pleasure and pain, and addictive behaviors.

The above actions may reduce the boosting properties of nicotine, offering relief from psychological symptoms of the addiction, such as anxiety and irritation.

It is possible that the action of CBD on the anandamide also reduces attention to contextual causes that may be involved in the persistence of nicotine consumption.

Vaping CBD as an Alternative to Smoking Tobacco

People increasingly become aware of the health dangers of smoking, hence the recent popularity of vaporization.

Vaping means heating a substance to specific temperatures where it starts to release concentrated vapor. This process doesn鈥檛 involve combustion, so many tobacco users are switching to vape pens to feed their addiction in a healthier way.

Indeed, the risk of smoking stems from the combustion of the material smoked, rather than the product itself.

However, when you switch from smoking tobacco to vaping it, you only change the consumption method. The addictive substance remains the same.

That鈥檚 why former tobacco smokers are turning to CBD vapes as a possible solution to their addiction. It is well-known that many tobacco consumers are able to cease their habit when they start vaping CBD.

According to some researchers, vaporizers can reduce cannabis and tobacco co-administration, resulting in a reduction of tobacco dependence and harms associated with its abuse.

If vaping CBD becomes more common in the future, the next generations might never be exposed to nicotine or tobacco in the first place.

CBD Oil vs CBD E-Liquid vs Vape Juice: What鈥檚 the Difference?

Some people are wondering if there鈥檚 a difference between CBD E-liquids and vape juice. These are actually different names used to describe a CBD-based liquid that can be consumed in a vape pen.

Vape pens are devices designed specifically for e-liquid consumption. They consist of a battery and cartridge that you can fill with any e-liquid or vape juice, including CBD.

CBD e-liquid is available in its pure form or mixed with existing flavors using terpenes or artificial flavorings.

But, can you vape regular CBD oil that you otherwise take under the tongue?

The answer is NO.

CBD concentrated oil in its traditional form is too viscous to be vaped in a vape pen. If you try doing so, it may cause your device to break down. CBD extracts are thinned with vegetable glycerin or propylene glycol (or a mix of both) to be compatible with vape pens.

Can You Substitute Nicotine for Another Stimulant so CBD Oil Can Be Taken?

In a study that analyzed the potential side-effects and drug-drug interactions with CBD use, results showed that interactions between CBD and stimulants may lead to reduced appetite, weight loss, and sleep disturbances (or insomnia).

Sleeping disorders may also result in mood swings and increased anxiety, which should also be managed with behavioral therapies or additional drugs as the potential of side effects is high according to the researchers.

Therefore, we suggest that you don鈥檛 take CBD oil with other stimulants unless studies have indicated otherwise (as with CBD and caffeine).

Interactions Between CBD and Stimulants Explained

• Smokefree.gov, a website run by the National Cancer Institute (NCI), reports that some people use smoking as a means of stress management or to cope with other unpleasant feelings. Unfortunately, nicotine, tar, and toxic gas are known as carbon monoxide are also released when tobacco is smoked (11).
• Meanwhile, CBD has remarkable anti-anxiety properties that can help users regulate emotions and manage stress without experiencing a euphoric high associated with marijuana consumption. This point refers to hemp-derived CBD (12).
• Specific data on nicotine and CBD interaction is not available, although one study found that CBD interactions with stimulants cause weight decrease, sleep disturbance, and reduced appetite (13).
• In a 2013 study published in the Addictive Behaviors journal, the authors noted that CBD may be a promising treatment for nicotine addiction (14).
• It鈥檚 best to consult a doctor experienced in cannabis use before replacing nicotine with CBD or before trying to fight nicotine dependence with CBD products.

Final Thoughts on CBD and Nicotine: Is CBD the Answer for Tobacco Addiction?

Giving up tobacco is challenging, but it鈥檚 one of the best things you can do for your health if you鈥檝e been struggling with this bad habit for quite some time already.

According to the University of California, San Francisco, 70% of smokers report a willingness to quit. However, many of them procrastinate with going cold turkey until they develop a severe tobacco-related disease such as stroke, cancer, or heart disease.

Nicotine addiction and the habit of smoking are treatable, so don鈥檛 be afraid if you鈥檝e already tried to quit in the past but to no avail. Those who receive counseling and medication during their attempt to ditch tobacco are more likely to win their battle than those who simply rely on their 鈥渟trong will.鈥�

CBD has been found to possess several properties that can help those struggling with nicotine addiction. Not only can CBD reduce cravings for cigarettes, but it can also ease the most common withdrawal symptoms of tobacco cessation, such as anxiety, weight gain, irritation, and sleep disturbances.

Although there has been no study that explicitly recommends CBD as a nicotine replacement, you can use the above information to help yourself effectively manage your addiction and live a nicotine-free life as a result of a holistic approach to addictive behaviors.

Do you take CBD to help yourself with nicotine cravings? Does it work? Let us know in the comment section below!

References:

1. Wiese, Beth, and Adrianne R Wilson-Poe. 鈥淓merging Evidence for Cannabis’ Role in Opioid Use Disorder.鈥� Cannabis and cannabinoid research vol. 3,1 179-189. 1 Sep. 2018, doi:10.1089/can.2018.0022
2. Morales, Marisela, and Antonello Bonci. 鈥淕etting to the core of addiction: Hooking CB2 receptor into drug abuse?.鈥� Nature medicine vol. 18,4 504-5. 5 Apr. 2012, doi:10.1038/nm.2722
3. Reiman A 2009. Cannabis as a substitute for alcohol and other drugs. Harm Reduction Journal. 6:35. doi: 10.1186/1477-7517-6-35
4. The World Health Organization. 鈥淎 guide for tobacco users to quit.鈥� (2014). Available at:
5. WHO Report on the Global Tobacco Epidemic, 2013.
6. Global Adult Tobacco Survey (The GATS Atlas) 鈥� section_read
7. American Cancer Society. 鈥淗ow to Quit Smoking or Smoke Less Tobacco?鈥� Available at:
8. Lopez-Quintero, C., Hasin, D. S., de los Cobos, J. P., Pines, A., Wang, S., Grant, B. F., Blanco, C. 2011. Probability and predictors of remission from life-time nicotine, alcohol, cannabis or cocaine dependence: Results from the national epidemiologic survey on alcohol and related conditions. Addiction, 106(3), 657-669; doi: 10.1111/j.1360-0443.2010.03194.x;
9. Prud’homme M, Cata R, Jutras-Aswad D. 2015. Cannabidiol as an intervention for addictive behaviors: A Systematic review of the evidence. Subst Abuse. 9:33-8. doi: 10.4137/SART.S25081.
10. Morgan, Celia J A et al. 鈥淐annabidiol reduces cigarette consumption in tobacco smokers: preliminary findings.鈥� Addictive behaviors vol. 38,9 (2013): 2433-6. doi:10.1016/j.addbeh.2013.03.011
11. Smokefree.gov. Stress and Smoking. Retrieved from .
12. Julien, R., Advokat, C., & Comaty, J. (eds.). (2011). A primer of drug action (12th ed.). New York: Worth Publishing.
13. Crippa et al. Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. J Psychopharmacol. 2011 Jan;25(1):121-30. doi: 10.1177/0269881110379283. Epub 2010 Sep 9. DOI: 10.1177/0269881110379283; Pellati F, Borgonetti V, Brighenti V, Biagi M, Benvenuti S, Corsi L. Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer. Biomed Res Int. 2018;2018:1691428. Published 2018 Dec 4. doi:10.1155/2018/1691428.
    1. Brown JD, Winterstein AG. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. J Clin Med. 2019;8(7):989. Published 2019 Jul 8. doi:10.3390/jcm8070989.

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Have you ever experienced that burning sensation after eating, especially after having something spicy?

Been there, done that.

Actually, we鈥檙e not alone in this.

According to statistics, 1 in 5 Americans experience heartburn, also known as acid reflux.

Most people tackle acid reflux with over-the-counter medications, but to no avail. Relief is only short-term, not to mention an array of unpleasant side-effects if you take these meds regularly.

It鈥檚 no wonder that people are looking for a healthier alternative to treat acid reflux, one that could address the problem properly, and without taking a toll on their health.

You may be wondering if CBD can treat acid reflux. After all, CBD has a long list of science-backed benefits; support for the gastrointestinal system is one of them.

CBD oil can be an effective treatment for many digestive problems, including acid reflux disease. In this article, we鈥檒l cover the potential benefits, explain how CBD works in the body to relieve heartburn and talk about CBD鈥檚 safety profile.

What is Acid Reflux?

The gastrointestinal system is one of the most complex and sensitive human organ systems. Upsetting your digestive network may lead to the overproduction of backflow of stomach acid 鈥� an event referred to as acid reflux.

Acid reflux happens when the stomach acid travels backward in your stomach area to your throat via the esophagus, which is a tube connecting the two. This backwash often damages the lining of the esophagus, causing irritation.

The discomfort experienced around the upper abdomen, which sometimes results in a painful burning sensation in the chest known as heartburn.

People with acid reflux suffer from heartburn after a decent hearty meal, drinking coffee, and alcohol.

On top of heartburn, acid reflux may be accompanied by difficulty in swallowing, nausea, or vomiting. It can also make your voice hoarse, cause sore throat, and a bad taste from the mouth.

What Causes Acid Reflux?

Acid reflux can have many causes, but most commonly it occurs when the muscles that control the tube between the stomach and esophagus fail to entirely close, allowing acids and food to flow back in the stomach. This can damage the tissue around that area.

Is Acid Reflux the Same as Gastroesophageal Reflux Disease (GERD)?

Yes and no.

From a medical standpoint, acid reflux is referred to as gastroesophageal reflux (GER). If this transforms into a more severe form that causes chronic symptoms, then it鈥檚 a Gastroesophageal reflux disease, commonly abbreviated to GERD.

GER and GERD share the same symptoms, including heartburn, but for GERD, the symptoms occur more than twice a week.

Furthermore, symptoms of GERD can include sour liquid, difficulty in swallowing, coughing, wheezing, and regurgitation.

Prevalence of Acid Reflux (Statistics)

In North America,. Mostly the younger population 鈥� 30鈥�39 years old 鈥� are more likely to suffer from the disease, contrary to a common belief that this problem is dominant among the older groups. (1)

The Healthcare and Utilization Project, a US government-run database of hospital care information reports that 60% of the population suffers from acid reflux some time during the year, with 20-30% experiencing the burn weekly.

Hospitalizations with either a primary or secondary GERD diagnosis increased by 216% between 1998 and 2005.

How Could CBD Help With Acid Reflux?

CBD can act on our gastroesophageal tract, but if you want to understand how this mechanism works, you need to take a closer look at the role of the Endocannabinoid System (ECS) in our well-being.

The ECS and its cannabinoid receptors regulate a vast range of biological functions, including the gastric function. A properly functioning endocannabinoid system ensures homeostasis 鈥� the state of balance between all processes that take place within your body.

Studies have shown that there are high concentrations of cannabinoid receptors in the gastrointestinal tract. Cannabinoids produced by the body, as well as those derived from cannabis plants, can regulate gastrointestinal motility, immunity and inflammation, gastric and intestinal acid secretion, emesis pathways, and nociception (2).

Below we go deeper into the two main areas of acid reflux that CBD can help with.

CBD Is an Anti-Inflammatory

While more clinical trials are needed to determine if CBD is a viable option for treating acid reflux, some studies suggest that CBD may play an important role in dealing with the symptoms of the condition, increasing the endocannabinoid system鈥檚 ability to combat inflammation and repair mucosal damage.

Apparently, CBD attaches to cannabinoid receptors located in the soft muscle tissue of the gastrointestinal system to calm involuntary muscle movements (peristalsis) that move food and waste. It also controls the secretion of hydrochloric acid, reduces the chances of it going back into the esophagus. In addition, CBD can curb inflammation and burn in the lining of the esophagus.

CBD Helps Relieve Pain

In a conducted in Sweden by scientists from AstraZeneca, the research team suggested that medical cannabis, including CBD, may help relieve the symptoms of acid reflux and GERD because 鈥渁ctivation of cannabinoid receptors CB1, CB2 produces analgesic [or pain relieving] effects in several experimental pain models, including visceral pain arising from the gastrointestinal tract.鈥� (3)

Since pain is a major problem with GERD, CBD鈥檚 painkilling properties have sparked attention in the medical community. An earlier conducted in 2009 has highlighted the analgesic and anti-inflammatory effects of CBD and its role in the modulation of CB1 and CB2 receptors (4).

How to Take CBD for Acid Reflux

CBD鈥檚 potential to treat acid reflux is promising, so it shouldn鈥檛 come to your surprise that so many people are considering it as an alternative treatment to OTC medications.

But how do you know how to take CBD for acid reflux to get the most out of your therapy?

Here鈥檚 a concise guide:

CBD Oil

CBD oil is the most common form of CBD. It comes in bottles with a glass dropper attached to them for precise dosing. CBD oil calls for sublingual administration. Simply put, the user needs to take it under the tongue, hold it in the mouth for about 60 seconds, and swallow. This way, CBD oil doesn鈥檛 have to pass through the digestive system and can produce its effects faster 鈥� usually within 15鈥�30 minutes after ingestion. The effects last for up to 6 hours.

CBD Capsules

Like all health supplements out there, CBD has an encapsulated form. CBD capsules are usually soft gels that contain a pre-measured dose of CBD. Capsules make supplementation more convenient because they take away the whole dropper mess, not to mention that you can easily take them on the go or keep them in your office cabinet without anybody raising brows. However, if you want to take CBD capsules for acid reflux, keep in mind that they will have a slower onset. Unlike CBD oil, capsules have to be metabolized in your digestive system in order to take effect. You鈥檒l need to wait anywhere between 40鈥�90 minutes to feel the difference in your symptoms.

CBD Edibles

CBD infused edibles are just like capsules, but they鈥檙e more enjoyable because of the different flavors they are infused with. The most popular type of CBD edibles are gummies; these little gummy bears contain a fixed amount of CBD to provide you with a fun way to take your daily dose of cannabidiol. Again, the effects are delayed due to the 鈥渇irst-pass effect鈥� in the liver.

CBD Vapes

Vaping is arguably the most efficient way to take CBD for acid reflux. It offers the highest bioavailability 鈥� up to 56% compared to 35% in tinctures and 20% in oral products 鈥� and produces the fastest effects. That鈥檚 because CBD is absorbed through the lung tissue right into the bloodstream. Usually, users report the first difference within 3鈥�5 minutes after inhalation. However, CBD vapes achieve peak effects relatively fast and disappear within 2-3 hours, so there are better options out there if you need long-lasting relief from your acid reflux symptoms.

CBD Dosage: How Much CBD Oil Should You Take for Acid Reflux?

There are no officially established dosage guidelines when it comes to CBD. The FDA has yet to analyze and establish the efficacy and safety of hemp-derived cannabidiol in order to rule out any further recommendations. Until then, CBD oil and other hemp products are categorized as health supplements and thus lack regulations when it comes to dosing, labeling, and manufacturing standards.

The best CBD dosage for acid reflux will depend on several factors, such as your age, gender, weight, metabolism, unique body chemistry, the severity of symptoms, and your prior experience with CBD.

It鈥檚 generally recommended to start with a low dose to assess your body鈥檚 response to CBD. An optimal starting dosage is between 1鈥�6 mg of CBD for every 10 pounds of a person鈥檚 body weight. After one week, you can reassess the effects and adjust the amount of CBD as needed.

Keep a dosage journal to write down different doses and times; this will help you get an accurate view of how they affect your acid reflux symptoms.

Is CBD Safe for Acid Reflux?

CBD has the upper hand over conventional anti-acid reflux medications because it lacks dangerous side effects associated with the latter. Numerous health organizations, including , have acknowledged CBD as a safe and effective compound. Studies show that CBD is well-tolerated in humans in doses up to 1,500 mg daily (5).

That being said, CBD has a few mild side effects, such as dry mouth, a temporary drop in blood pressure, dizziness, or changes in appetite. Most people, however, don鈥檛 experience these side effects at regular doses.

Potential CBD-drug interactions are the main concern of people who want to incorporate CBD into their daily routine. CBD engages with the same group of enzymes that breaks down active ingredients in pharmaceutical medications. If you鈥檙e taking any prescription or OTC meds, be sure to consult your doctor in order to avoid these interactions and collateral side-effects.

Conclusion: Is CBD a Viable Option for Acid Reflux?

Acid reflux is an unpleasant condition in which the stomach gets upset, leading to backflow or 鈥渞eflux鈥� of gastric acid to the esophageal tract. Acute acid reflux can turn into a chronic one due to a poor diet and bad lifestyle choices (e.g. smoking cigarettes and drinking alcohol). When that happens, it results in GERD, which is a chronic disease.

CBD鈥檚 interaction with the endocannabinoid system results in the softening of the gastrointestinal muscles and protects their lining against damage. Improved peristalsis of these muscles prevents fluid backflow to the esophagus, also regulating acid production.

CBD is a promising compound when it comes to treating acid reflux, although we need more longitudinal studies to draw definite conclusions on this subject. If you鈥檙e considering a CBD treatment for acid reflux, you should seek advice from a doctor expert on cannabis.

Do you take CBD for acid reflux?

References:

1. Yamasaki, T. et al. 鈥淭he Changing Epidemiology of Gastroesophageal Reflux Disease: Are Patients Getting Younger?鈥�. Journal of Neurogastroenterology and Motility (2018), 24(4): 559-569.
2. Aviello, G et al. 鈥淐annabinoids and gastrointestinal motility: animal and human studies.鈥� European review for medical and pharmacological sciences vol. 12 Suppl 1 (2008): 81-93.
3. Gotfried, J., Kataria, R., and Schey, R. 鈥淩eview: The Role of Cannabinoids on Esophageal Function 鈥� What We Know Thus Far.鈥� Cannabis and Cannabinoid Research (2017), 2(1):252鈥�258.
4. Elikottil, J. et al. 鈥淭he Analgesic Potential of Cannabinoids鈥�. Journal of Opioid Management (2009), 5(6): 341鈥�357.
5. The World Health Organization. 鈥淐annabidiol (CBD): Critical Review Report鈥�. Expert Committee on Drug Dependence, Fortieth Meeting, Geneva, 4鈥�7 June 2018. Source:

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Cannabis compounds are more often prescribed by doctors to treat serious chronic conditions. Cannabinoids like CBD and THC have been highlighted as potent anti-inflammatory agents, neuroprotectants, painkillers, and antioxidants.

CBD can also regulate our blood sugar levels and help with metabolism on many levels, according to recent research. Not only does CBD promote fat-browning, but it can also curb cravings for high-calorie food and reduce stress levels, preventing people from eating compulsively.

But does CBD have a direct impact on diabetes? Can you take it as a diabetes treatment instead of conventional medications? Are CBD and metformin a good match?

Metformin is a common anti-diabetes medication that doctors prescribe to lower blood sugar levels in their patients. The idea of combining these two compounds is tempting, especially if your current treatment doesn鈥檛 bring satisfying results.

Let鈥檚 take a look at the current situation of CBD in treating diabetes 鈥� and how it interacts with meds such as metformin.

What is Metformin?

Metformin is an FDA-approved medicine commonly prescribed to treat type 2 diabetes. Doctors often recommend this drug on its own or prescribe it along with other diabetes medications to manage high blood sugar levels.

Metformin has proven to be an effective treatment for the majority of diabetes complications; it can also prevent diabetes in high-risk individuals. Despite some adverse reactions reported by individual patients, the benefits definitely outweigh the potential side effects.

What is CBD and How Does It Impact Glucose Levels?

CBD is short for cannabidiol, a phytocannabinoid present in the Cannabis sativa plant. Unlike THC, CBD is non-intoxicating, so it won鈥檛 get you high. However, it still has a plethora of therapeutic properties, some of which are related to CBD鈥檚 impact on our metabolism and blood glucose levels.

In a conducted on diabetic mice, CBD treatment showed to be capable of lowering the chances of diabetes in the subjects. The research team administered a daily dose of 5 mg/kg CBD to the mice for ten weeks at least five times a week (1).

, from 2018, has analyzed the mechanism of action of phytocannabinoids as anti-obesity and anti-diabetic compounds. The study highlighted CBD as the potential aid in the treatment of insulin resistance triggered by obesity and diabetes (2).

CBD and Metformin: Potential Interactions

Considering what we鈥檝e said about Metformin and CBD so far, one could assume that it would be beneficial to combine them. However, no study has yet confirmed whether or not these products are compatible with one another.

CBD is metabolized by the same system of enzymes that breaks down active ingredients in medications. In past research, CBD has been highlighted as a potent inhibitor of cytochrome P450 enzymes. In other words, CBD can compromise the liver鈥檚 ability to process other drugs when taken along with them.

The above interaction could result in increased or decreased levels of active drug ingredients in the blood, causing problems associated with being subtherapeutic or, on the contrary, toxic.

CBD鈥檚 interaction with CYP450 can change the way it affects the endocannabinoid system (ECS). The ECS is the major regulatory network found in humans and animals that regulates the activity of other systems and organs, including the central nervous system.

Metformin has a few side effects on its own, so the more medication circulates in your bloodstream, the higher the risk you will experience adverse reactions. Although these side-effects are not severe, they may lead to a condition known as lactic acidosis. This disorder includes symptoms like muscle pain, dizziness, drowsiness, chills, and breathing difficulties.

Since there is no clear indication of whether using CBD and metformin is dangerous, it鈥檚 always better to err on the side of caution and consult your doctor about applying CBD in your routine before buying any CBD product.

A doctor experienced in treating people with cannabinoids should be able to point you in the right direction.

Can You Substitute Metformin with Another Antihyperglycemic to Take CBD Oil?

Insulin is another antihyperglycemic commonly used to lower high blood sugar to diabetics. Doctors often prescribe special injections to administer the compound intravenously.

In a conducted on 62 participants with type 2 diabetes, scientists have found that a combination of THC and CBD can lower insulin resistance while increasing its potency in the body. These same patients weren鈥檛 treated with insulin and tolerated both CBD and THC well (3).

A from 2018 shows that low-dose CBD can increase glucose uptake, decrease fat accumulation, and reverse insulin resistance in rats (4). This may be an indication of further clinical trials in humans. Despite being effective in rodents, CBD may not work the same in human subjects, so it鈥檚 necessary to test its efficacy on a broader scale.

Can You Replace Metformin with CBD?

Research has yet to prove whether or not CBD is a safe alternative to metformin use in diabetic humans. Most of the studies on CBD鈥檚 effect on diabetes were conducted on rodent models.

For example, one 2016 study on non-obese diabetic mice has shown that CBD can lower the risk of diabetes by altering the response in the immune system in rodents. The non-treated mice had an 86% probability of developing diabetes, while subjects that took CBD only had 30% (5).

The administration of CBD also significantly lowered plasma blood levels of the pro-inflammatory cytokines, while also lowering the possibility of inflammatory liver damage 鈥� the underlying cause of type 1 diabetes.

Finally, a on diabetic rats tested the therapeutic properties of CBD in both ischemic disease models and diabetes (6). The study revealed that CBD reduces neuropathic pain, improves memory performance, and reduces hippocampal levels of inflammation markers (6).

According to cannabis experts, CBD-rich products can be used to target the symptoms of diabetes. Since there are limited data on CBD鈥檚 efficacy in the human models of type 1 and type 2 diabetes, it鈥檚 always best to seek professional advice from a doctor before considering replacing metformin with CBD oil or edibles.

Drugs That Can Interact with Metformin

Metformin consists of positively charged molecules (cations) that can be processed by the same enzymes as similarly charged drugs for renal secretion through cation transporters found in the kidneys.

Cationic medications that can interact with metformin include quinidine, procainamide, trimethoprim, digoxin, and vancomycin. These drugs can be purchased over the counter for heartburn and may contribute to a case of metformin-associated lactic acidosis (MALA).

Here鈥檚 the list of other medications that can interact with metformin:

• Calcium channel blockers
• Corticosteroids
• Diuretics
• Estrogen and oral contraceptives
• Phenytoin
• Thyroid medications

Combining the aforementioned drugs with metformin may result in too-low blood sugar levels in the body. Patients need to monitor their glucose levels frequently to avoid sudden changes.

The following drugs can reduce the kidneys鈥� capacity to flush metformin from the blood and thus cause lactic acidosis:

• Cimetidine
• Dolutegravir
• Ranolazine
• Vandetanib

We encourage you to consult a doctor to determine if these drug combinations are worth the risk. There may be a safer alternative that doesn鈥檛 entail the same risk of danger.

If you want to avoid increasing the risk of lactic acidosis when using metformin, it鈥檚 better to abstain from taking carbonic anhydrase inhibitors such as topiramate or acetazolamide.

Lactic acidosis may be detected early if patients taking CAIs together with metformin are monitored during their treatment.

Your doctor can also change the dosage or even suggest a safer, alternate medication to manage your blood glucose levels if metformin itself has too heavy side-effects on your health.

People changing immediate-release to extended-release metformin pills may experience fewer cases of diarrhea, as reported by a study in 2004.

Anemia and vitamin B-12 deficiency are also possible in people who have been taking metformin for at least a few months. Supplementing iron and vitamin B-12 may help prevent these problems if they occur in long-term metformin users.

What Experts Say 口交视频 CBD and Metformin

Allan Frankel MD, an experienced physician and expert in in Santa Monica, believes that CBD and metformin can be taken in tandem, but it requires proper care from your doctor. He also claims that patients can become able to ditch their type 2 diabetes medications thanks to using CBD.

鈥淲e have seen a substantial lowering of their [CBD patients] glucose levels in those with Type II Diabetes including several patients鈥� Hemoglobin A1C levels normalize so they are able to stop their Type II Diabetes medications, he said.鈥�

However, CBD can cause blood glucose levels to drop too much due to their combined effects.

聽鈥淭he first time I saw this with a Diabetic, he called me after having some hypoglycemic episodes while taking CBD in addition to his Metformin, Frankel continues. 鈥淚 told him to stop his Metformin and continue his CBD. His glucose levels normalized and he remained off Metformin.鈥�

According to Frankel, CBD can also raise good cholesterol levels, while lowering bad cholesterol levels by stabilizing a patient鈥檚 blood sugar levels. He says he has seen patients ditching the statin once they have seen consistent improvements in their cholesterol levels.

On top of that, CBD 鈥� especially when combined with THC 鈥� can improve the side effects caused by poorly managed diabetes, including neuropathic pain.

鈥淲e have also seen improvements ranging from apparent stabilization of macular degeneration and help with neuropathic pain. Sometimes combined with THC, CBD is an avascular and renal protectant.鈥�

To sum up, using CBD provides a multipronged approach for treating diabetes. It can be taken in tandem with metformin, but only under the observation of your doctor. Monitoring blood glucose levels is essential for avoiding unpleasant side-effects, such as hypoglycemia. On top of blood sugar management, CBD can balance cholesterol levels and speed up metabolism.

鈥淚 believe this is all happening on a number of metabolic levels, such as bringing the sensitivity of insulin back to normal,鈥� Frankel concludes.

Final Thoughts on CBD and Metmorfin

Metformin is an FDA-approved prescription drug for the treatment of type 2 diabetes. Patients take it on its own or with other prescription drugs with high sugar levels in the blood.

While metformin can effectively prevent diabetes in high-risk individuals, while also addressing most of its symptoms, it may cause a few adverse reactions. Fortunately, most users report that the benefits outweigh the potential side-effects.

People seeking natural treatments for diabetes often turn to CBD as their go-to supplement. CBD interacts with the human endocannabinoid system whose receptors are known to regulate blood sugar levels on top of many other metabolic functions.

Studies from animal models have demonstrated CBD鈥檚 efficacy in treating the symptoms of diabetes and managing the condition itself. While more human research is needed to confirm these findings, they are, at least to say, promising when it comes to contemporary diabetes treatments.

CBD and metformin can interact with one another because they are processed by the same system of enzymes. CBD is the inhibitor of these enzymes, meaning it can either increase or decrease the concentration of metformin in the bloodstream. This, in turn, can result in toxicity or subtherapeutic effects depending on the scenario.

As there鈥檚 no clear indication regarding the risk of taking CBD with metformin, it鈥檚 best to consult a physician who is experienced in complementary treatments. Medical advice from a professional will help you avoid potentially dangerous interactions and get the most out of your diabetes routine.

Do you take CBD and metformin together?

References:

1. Lehmann, Christian et al. 鈥淓xperimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes.鈥� Clinical hemorheology and microcirculation vol. 64,4 (2016): 655-662. doi:10.3233/CH-168021
2. Clark, T et al. 鈥淭heoretical Explanation for Reduced Body Mass Index and Obesity Rates in Cannabis Users.鈥� Cannabis and Cannabinoid Research, vol 3,1 (2018): 259鈥�271.
3. Frisher, M et al. 鈥淭he Role of Cannabis and Cannabinoids in Diabetes鈥�. The British Journal of Diabetes & Vascular Disease, vol 10,6 (2010): 267鈥�273.
4. Ramlugon, S., Levendal, R.A., and Frost, C.L. 鈥淭ime-dependent Effect of Phytocannabinoid Treatments in Fat Cells鈥�. Psychotherapy Research, vol 32,3 (2018).
5. Lehmann, Christian et al. 鈥淓xperimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes.鈥� Clinical hemorheology and microcirculation vol. 64,4 (2016): 655-662. doi:10.3233/CH-168021
6. Santiago, Amanda Nunes et al. 鈥淓ffects of Cannabidiol on Diabetes Outcomes and Chronic Cerebral Hypoperfusion Comorbidities in Middle-Aged Rats.鈥� Neurotoxicity research vol. 35,2 (2019): 463-474. doi:10.1007/s12640-018-9972-5

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The reports from the World Health Organization (WHO) estimate that asthma affects 339 million people worldwide. It has definitely earned a spot as one of the chronic ailments that could use an effective, natural treatment.

With CBD becoming more and more popular, some asthmatics have decided to give it a leap of faith. Many people, however, are concerned whether CBD and asthma are actually a good match.

CBD (cannabidiol) is the non-intoxicating compound of hemp or marijuana plants. It has created the latest gold-rush in the wellness industry thanks to its versatility and an excellent safety profile.

Hemp-derived CBD is legal in all 50 states under the 2018 Farm Bill. You can find it over the counter in health retail outlets, dispensaries, and vape shops. It comes in tinctures, capsules, edibles, topicals, vapes, and even pet products.

But can CBD actually help asthma sufferers reduce the symptoms of their illness?

Let鈥檚 dive into this!

Understanding Asthma

Asthma is a common chronic disorder of the lungs that starts in the respiratory airways due to inflammation and swelling. The lung airways become narrowed, constricted, and filled with mucus, enabling the person to breathe properly.

There are several types of asthma. Allergic asthma, which is the overreaction of the immune system when allergens appear, is the most common one. Allergens that may cause asthma include pollen, dust mite excrements, mold spores, cold, germ-ridden dirt, and pet dander.

Asthmatics accounts for about 8% of the U.S. general population. 10 Americans are diagnosed with the condition every day, as reported by the Centers for Disease Control and Prevention (CDC).

What Are the Symptoms of Asthma?

Whether your asthma is chronic or induced by allergy, people with the condition typically experience a similar range of symptoms, including:

• Shortness of breath
• Wheezing
• Difficulty falling asleep
• Coughing
• Chest pain and/or tightness

The above symptoms usually vary between individuals, as they often become noticeable at certain times, such as when exercising, during cold weather, or when exposed to allergens.

For some patients, asthma is a mild ailment. However, others may experience serious health issues, such as severe asthma attacks which can put a person鈥檚 life at risk.

An asthma attack refers to an episode that involves a sudden worsening of symptoms. These flare-ups, as people usually call them, contribute to roughly 2 million emergency room visits every year and can seriously deteriorate the patient鈥檚 quality of life. Without proper treatment and immediate medical care, an asthma attack can lead to death.

How is Asthma Diagnosed?

Physicians usually check for symptoms as well as order a few simple tests to diagnose asthma. You鈥檙e not likely to see a respiratory specialist unless your doctor deems it necessary due to a supposedly another underlying disorder.

Physical examination is the most common method to check if a person has asthma. Your doctor may ask you the following questions:

• What symptoms are you experiencing?
• When and how often do these symptoms occur?
• What else might be triggering them?
• Do any of your close relatives have asthma?
• Are you allergic or have conditions like eczema or COPD?

Another way to diagnose asthma is to run a lung function test, such as the peak flow test or spirometry.

The peak flow will measure the force with which you can exhale air from the lungs. If you score below normal readings, it鈥檚 often an indicator that your lungs aren鈥檛 functioning properly. It can also mean that you have asthma.

Spirometry requires you to blow into a gadget that will measure how much air you can both inhale and the force and speed with which you can expel the air. This test provides an overall image of how your lungs function.

Other asthma tests include:

• FeNO Test: it measures the nitric oxide levels of your breath (a common marker of lung inflammation).
• Allergy Test: these are done to establish if your asthma is caused by allergies.
• Imaging Tests: you may be asked to take a CT scan or a chest X-ray scan to take any infections out of the equation.
• Sputum Eosinophils: it checks for the presence of specific white blood cells that amplify asthma symptoms.
• Methacholine Challenge: this test checks for signs of hidden or asymptomatic asthma.
• Provocative Testing: provocative tests allow a physician to check for airway constriction or obstruction before and after you have been exposed to physical activity or cold temperatures.

Why Are Some People Turning to CBD for Asthma?

Managing the symptoms of asthma isn鈥檛 a walk in the park. It requires you to take an all-around approach to your lungs鈥� health. While there are certain prescription medications that you can take to keep asthma attacks at bay and ease symptoms, many of them have dangerous side effects that can be discouraging.

Regular use of preventive inhalers can leave you with a sore throat, tatty voice, and oral fungal infections. Substances like zileuton, which are leukotriene modifiers, may sometimes increase the risk of depression or cause hallucinations and even suicidal thoughts.

Could CBD be the proverbial miracle in the bottle for asthmatics?

There鈥檚 an emerging body of research targeting CBD鈥檚 potential as an alternative treatment for asthma symptoms. Some studies have actually suggested that CBD may benefit asthmatics.

The attention of the medical community stems from their curiosity about whether CBD can offer relief for the symptoms of asthma rather than curing it.

How CBD Can Help with Asthma

While cannabis as the whole plant has been on the radar of medical researchers for quite some time now, it鈥檚 CBD that has recently become the apple in their eye 鈥� and for good reasons.

Here鈥檚 how taking CBD can help with your asthma symptoms.

CBD Oil Is an Anti-inflammatory

Inflammation in the lungs is the major contributor to asthma attacks. When an asthma sufferer gets exposed to allergens or other irritants, the immune system sends out an inflammatory response.

Inflamed airways may lead to muscle spasms and secretion of too much mucus. The outcome is dangerous because clogged, narrowed airways filled with mucus make breathing in and out extremely difficult.

This is where CBD may shine.

Scientists have attributed CBD鈥檚 anti-inflammatory properties to its interaction with the endocannabinoid receptor CB2, which helps reduce the levels of pro-inflammatory cells such as C fibers or mast cells.

A published in the European Journal of Pharmacology found that CBD use may reduce inflammatory reactions and promote the recovery of lung function in patients with allergy-induced asthma (1).

Similar findings were reported a few years earlier in a (2), in which the research team concluded that CBD and other cannabinoids are potent anti-inflammatory agents that can help people with respiratory disorders, inflammatory pain, and ischemic stroke.

CBD Oil Is an Antispasmodic

During an asthma attack, individuals experience spasms that affect the bronchi and bronchioles due to contracting the muscles in the lungs, which makes breathing difficult and causes wheezing.

Recent research has shown that CBD may help relieve muscle spasticity. By reducing muscle spasms, it helps open the airways, easing asthma symptoms. This trait has also been proven in the studies aimed at determining the therapeutic potential of CBD for epilepsy.

In a (3) testing the efficacy of Sativex 鈥� an oral spray containing THC and CBD in 50:50 ratio 鈥� on multiple sclerosis patients, researchers reported considerable improvements in both muscle spasticity and mobility.

Although more large-scale clinical trials are needed to establish CBD鈥檚 efficacy for asthma, the cannabinoid offers potential benefits for MS patients who experience muscle spasms. It鈥檚 possible that CBD may also help relax the muscles in the lungs and allow asthma sufferers to breathe easily as a result. Still, we suggest that you consult a doctor before taking CBD oil for asthma.

CBD Oil May Reduce Asthma Drug-Induced Anxiety

Anxiety can seriously impair one鈥檚 quality of life by taking a toll on your mental health and well-being. The majority of asthma medications like traditional inhalers are infused with stimulants. These compounds, although they are effective bronchodilators, can cause or exacerbate anxiety.

CBD has been recognized by its remarkable anxiolytic (anti-anxiety) properties in several experimental models, so there鈥檚 a chance that you can benefit from it in conjunction with conventional treatments to prevent anxious episodes (4).

CBD vs Conventional Asthma Treatments

There are two types of medications for asthma sufferers depending on your individual situation: short-term medications and long-term treatments.

Short-term medications include:

• Rescue inhalers
• Nebulizers
• Anti-inflammatories
• Corticosteroids

While rescue inhalers and nebulizers are relatively safe, regular use of anti-inflammatory drugs and corticosteroids can have adverse side effects, and as such, they should be used on a short-term basis.

The above short-term solutions are often taken in conjunction with some of the following long-term medications:

• Leukotriene receptor antagonists (LTRAs)
• Long-acting beta-agonists
• Theophylline
• Inhaled corticosteroids
• Combined inhalers
• Allergy medications
• Injections (for severe asthma cases)

If nothing else seems to help, a doctor may recommend bronchial thermoplasty as a last-resort option. This special procedure is rare but effective and relatively safe.

Home remedies are often used in tandem with conventional asthma treatments to prevent intensification of symptoms and flare-ups. Common home remedies include essential oils from herbs, caffeinated drinks, and mustard oil (as an ointment).

Is CBD Safe for People with Asthma?

The use of CBD for asthma brings a lot of excitement considering the anti-inflammatory and bronchodilating potential of CBD. Early studies suggest that CBD may help reduce anxiety, inflammation, and muscle spasticity, induced by conventional medications.

CBD has a very good safety profile. It is well tolerated in humans even in doses as high as 1,500 mg daily. However, scientists haven鈥檛 investigated the safety of CBD specifically in relation to asthma.

The biggest concern shared by doctors is about CBD鈥檚 ability to interact with other drugs. CBD is metabolized by the same group of enzymes that process active ingredients in pharmaceutical medications. Therefore, we suggest that you consult with your doctor before adding CBD oil to your daily routine.

Experts suggest that people with asthma choose CBD products that don鈥檛 involve inhalation. Smoking or vaping CBD isn鈥檛 recommended due to the risk of large air sacs growth in the airways and other lung cavities.

How Should You Take CBD for Asthma?

This is the most challenging part of using CBD when you have asthma. We鈥檝e already made it clear that smoking and vaping are out of the question, but what鈥檚 the best way to take CBD for asthma?

Choosing the right dosage and form of consumption often involves several factors, such as:

• Your body weight
• Your metabolism
• The type of asthma you have
• Your previous experience with CBD
• The intensity and frequency of your asthma symptoms
• Other medications you might be taking.

Again, it鈥檚 of the utmost importance that you work with your doctor to determine which CBD product is right for your situation.

Another thing to keep in mind is the cannabinoid spectrum. CBD products are either full-spectrum, broad-spectrum, or isolates. Full-spectrum CBD is made using the entire plant and contains all the compounds you can find in hemp, including cannabinoids, terpenes, flavonoids, fatty acids, vitamins, and minerals. These compounds work synergistically to increase the efficacy of CBD oil; this phenomenon is known as the entourage effect. Broad-spectrum CBD is pretty much the same, but without any THC inside the end product. Isolate is just pure CBD that has been separated from other compounds. Isolates are THC-free; they鈥檙e also odorless and flavorless, which makes them more versatile. However, they don鈥檛 promote the entourage effect.

All things considered, here are the most popular forms of CBD that you can use for asthma:

CBD Oil Drops

CBD oil is the most common form of CBD. It is sold in glass bottles with a dropper attached for precise dosing. CBD oil includes a hemp extract suspended in a carrier oil such as hemp seed oil, MCT oil, or olive oil.

CBD oil drops are available in a wide range of potency options and several different flavors. You can take them sublingually by placing a few drops under your tongue and holding them there for 60 seconds before swallowing 鈥� or add it to your food.

The area under the tongue is chock-full of tiny blood vessels which absorb CBD rapidly into the bloodstream. When taken this way, CBD doesn鈥檛 need to pass through the digestive system. The first effects usually come within 15鈥�30 minutes after ingestion and last up to 6 hours.

CBD Capsules and Pills

CBD is also available in standard capsule form which may be useful for consistent supplementation with pre-measured doses of CBD. However, CBD capsules must go through the first-pass effect, which reduces their bioavailability. Only up to 20% of ingested CBD will reach your bloodstream.

It will usually take 40鈥�90 minutes to experience the effects of CBD capsules. But on the other hand, they will last longer than those from CBD oil 鈥� even 10 hours.

CBD Edibles

Edibles have become extremely popular recently as a way to consume CBD. They range from gummies to cookies, chocolates, mints, truffles, or even lollipops.

CBD edibles are tasty, discreet, portable, and generally cheaper than CBD oil. Gummies are commonly used by asthmatics because they provide a fixed-dose in each gummy. The dosage ranges from 5 mg to 50 mg of CBD per piece.

Similar to capsules, edibles must pass through the digestive system, so you might have to wait up to 2 hours for the effects to be felt.

It goes without saying that edibles aren鈥檛 the best go-to consumption method due to the delayed onset, but if you value discretion in your CBD routine for prevention, they are worth a try.

CBD Topicals

CBD topicals is an umbrella term for products that you apply directly to the skin. You can find CBD in salves, creams, gels, ointments, balms, lotions, and transdermal patches.

Topical products are designed to target localized problems, such as inflammation and pain in the joints and muscles. Some of them combine CBD with other therapeutic ingredients, such as camphor, lavender, peppermint, menthol, or eucalyptus oil.

You should use CBD topicals directly on where you need relief. Asthma patients can benefit from topicals by rubbing a cream or salve on the chest area to help open the airways and relieve breathing difficulties.

Final Thoughts: Is CBD Oil a Viable Option for Asthma?

Asthma is a chronic condition that 鈥� when left untreated 鈥� can be life-threatening. Its tell-tale symptoms include wheezing, coughing, shortness of breath, and tightness in the chest.

There is currently no cure for asthma, which means a treatment is aimed at reducing the symptoms and preventing attacks. With inhalers, pills, steroids, injections, and other asthma medications, it鈥檚 easy to manage the symptoms and live a normal life.

However, conventional medications have side effects, ranging from anxiety to depression and occasionally more severe symptoms like suicidal thoughts. A growing number of asthma sufferers are turning to CBD as a safe alternative to deal with symptoms without side effects. Some of them have seen the positive effects of combining CBD with asthma medication.

According to a recent report from the WHO, CBD is generally safe, well-tolerated, and effective, although no studies have been conducted with regards to its efficacy in asthma patients.

Moreover, CBD has a bronchodilatory effect, which can help reduce muscle spasms and relax the lungs. Taking full-spectrum CBD oil may both improve lung function and make breathing easier.

If you want to start taking CBD for asthma, we encourage you to consult your doctor in order to avoid potential drug interactions. From there, you can choose the best form of CBD for your individual situation. However, remember that vaping and smoking CBD aren鈥檛 recommended, as they pose a risk of exacerbating your asthma symptoms.

References:

1. Vuolo, Francieli et al. 鈥淐annabidiol reduces airway inflammation and fibrosis in experimental allergic asthma.鈥� European journal of pharmacology vol. 843 (2019): 251-259. doi:10.1016/j.ejphar.2018.11.029
2. Pini, Alessandro et al. 鈥淭he role of cannabinoids in inflammatory modulation of allergic respiratory disorders, inflammatory pain and ischemic stroke.鈥� Current drug targets vol. 13,7 (2012): 984-93. doi:10.2174/138945012800675786
3. Russo, M., Calabro, R.S. and Bramanti, P. 鈥淪ativex in the Management of Multiple Sclerosis-Related Spasticity: Role of the Corticospinal Modulation.鈥� Neural Plast (2015).
4. Shannon, S. et al. 鈥淐annabidiol in Anxiety and Sleep: A Large Case Series.鈥� The Permanente Journal (2019), 23: 18鈥�041.

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