{"id":3728,"date":"2020-03-04T22:23:42","date_gmt":"2020-03-04T22:23:42","guid":{"rendered":"http:\/\/www.weednews.co\/?p=3728"},"modified":"2022-01-20T01:34:55","modified_gmt":"2022-01-20T01:34:55","slug":"cbd-oil-for-seizures","status":"publish","type":"post","link":"https:\/\/www.weednews.co\/cbd-oil-for-seizures\/","title":{"rendered":"Best CBD Oil for Seizures and Epilepsy: Top Brands Reviews in 2022"},"content":{"rendered":"<p>June 25, 2018, was a historic moment for cannabis. On that day, the FDA approved the first CBD-based drug Epidiolex.<\/p>\n<p>Before making it to the market in the US, Epidiolex has been tested in many clinical studies around the world regarding the use of cannabis as a treatment for epilepsy.<\/p>\n<p>The fact Epidiolex was approved by a federal agency is a huge step forward for legalization. In the US, people are still struggling to access the plant for medical purposes; the legal struggle derives from misunderstandings concerning the qualifications for joining a state\u2019s medical marijuana program.<\/p>\n<p>At the time of this writing, the easiest way to get legal CBD oil in the USA is to buy hemp-derived products that have 0.3% THC or less.<\/p>\n<p>In this article, we\u2019ll look at the larger picture when it comes to using CBD oil for epilepsy. We\u2019ll also highlight <a href=\"https:\/\/www.weednews.co\/best-cbd-oil\/\" target=\"_blank\" rel=\"noopener noreferrer\">the most reliable manufacturers on the market<\/a> so that you can avoid sketchy businesses.<\/p>\n<h2><strong>CBD Oil for Seizures and Epilepsy: Best Brands in 2022<\/strong><\/h2>\n<p>Finding high-quality CBD oil can be difficult if this is your first purchase.<\/p>\n<p>Where does a company source its CBD from?<\/p>\n<p>Is their hemp organic?<\/p>\n<p>What solvents have been used for making your CBD oil?<\/p>\n<p>What are third-party lab reports and how should you read them?<\/p>\n<p>These are just the basic questions you should answer when searching for CBD oil online.<\/p>\n<p>We\u2019ve done the research part for you. After trying 30+ CBD brands, we\u2019ve selected the top 5 companies that sell premium, full-spectrum CBD that has been tested for potency and purity.<\/p>\n<p>Read on to find out why these are the best CBD oils for seizures and epilepsy.<\/p>\n<h3><strong>1. <a href=\"https:\/\/royalcbd.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">Royal CBD<\/a><\/strong><\/h3>\n<p><a href=\"https:\/\/royalcbd.com\/cbd-oil\/\" target=\"_blank\" rel=\"nofollow noopener\"><img class=\"aligncenter size-full wp-image-7605\" src=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2021\/01\/RoyalCBD_2500mg_CBD_Oil.jpg\" alt=\"Royal CBD Oil 2500mg\" width=\"450\" height=\"450\" srcset=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2021\/01\/RoyalCBD_2500mg_CBD_Oil.jpg 450w, https:\/\/www.weednews.co\/wp-content\/uploads\/2021\/01\/RoyalCBD_2500mg_CBD_Oil-300x300.jpg 300w, https:\/\/www.weednews.co\/wp-content\/uploads\/2021\/01\/RoyalCBD_2500mg_CBD_Oil-150x150.jpg 150w, https:\/\/www.weednews.co\/wp-content\/uploads\/2021\/01\/RoyalCBD_2500mg_CBD_Oil-100x100.jpg 100w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/a><strong>Product Details<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Potency<\/strong><\/td>\n<td>250 mg \u2013 2500 mg<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Flavors<\/strong><\/td>\n<td>Natural, Berry, Mint, Vanilla<\/td>\n<\/tr>\n<tr>\n<td><strong>CBD per serving<\/strong><\/td>\n<td>8.3 mg \u2013 83.3 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4><strong>Why Royal CBD is the Best CBD Oil for Seizures and Epilepsy<\/strong><\/h4>\n<p>Royal CBD is a relatively new brand. Launched in late 2017, the company started selling premium CBD extracts from organic hemp and quickly made its name in the industry thanks to the quality of its products. This brand combines simplicity with transparency, which is not common for new companies that try to sell everything but the kitchen sink. Royal CBD offers traditional forms of cannabidiol, including CBD oil drops, capsules, gummies, and topicals.<\/p>\n<p>Royal CBD uses organic hemp and makes its products with CO2 extraction, which is the golden standard for making CBD products. These are full-spectrum extracts, meaning they resemble the original phytochemical profile of the source plant. All of the company\u2019s products have been tested in a third-party laboratory for potency and purity; they come with Certificates of Analysis proving their content.<\/p>\n<p>The Royal CBD oil is available in 4 potency options, including 250 mg, 500 mg, 1000 mg, and 2500 mg. On top of the natural flavor, you can choose from flavors like Berry, Mint, and Vanilla. If you want the best option for seizures, I recommend the 2500 mg potency. This CBD oil carries 83.33 mg of CBD in each mL; it\u2019s a decent strength for neurological issues and saves you more money in the long run.<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Pros<\/strong><\/td>\n<td><strong>Cons<\/strong><\/td>\n<\/tr>\n<tr>\n<td>\n<ul>\n<li>Made from locally grown organic hemp<\/li>\n<li>Extracted with supercritical CO2<\/li>\n<li>Infused with full-spectrum CBD<\/li>\n<li>Available in 4 strengths and flavors<\/li>\n<li>Up to 2500 mg of CBD per bottle<\/li>\n<li>3rd-party tested for potency and purity<\/li>\n<li>Great natural flavor<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li>Not available in local CBD stores (this may soon change)<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><strong>2. <a href=\"https:\/\/goldbee.com\/cbd-oils\/\" target=\"_blank\" rel=\"nofollow noopener\">Gold Bee<\/a><\/strong><\/h3>\n<p><a href=\"https:\/\/goldbee.com\/products\/cbd-oil\/\" target=\"_blank\" rel=\"nofollow noopener\"><img class=\"wp-image-5909 size-full aligncenter\" src=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/08\/gold-bee-cbd-oil-1.jpg\" alt=\"Gold Bee 1200mg CBD oil in white background\" width=\"450\" height=\"450\" srcset=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/08\/gold-bee-cbd-oil-1.jpg 450w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/08\/gold-bee-cbd-oil-1-300x300.jpg 300w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/08\/gold-bee-cbd-oil-1-150x150.jpg 150w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/08\/gold-bee-cbd-oil-1-100x100.jpg 100w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<h4><strong>Product Details<\/strong><\/h4>\n<table>\n<tbody>\n<tr>\n<td><strong>Potency<\/strong><\/td>\n<td>300 \u2013 1200 mg<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Flavors<\/strong><\/td>\n<td>Natural, Honey<\/td>\n<\/tr>\n<tr>\n<td><strong>CBD per serving<\/strong><\/td>\n<td>10 mg \u2013 40 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4><strong>口交视频 Gold Bee<\/strong><\/h4>\n<p>My second-best pick comes from California too. Gold Bee is another premium company that offers CBD products from organic hemp. The company\u2019s mission is to shed stigma from hemp, which was unjustly demonized for the past century, and provide the health benefits of CBD to all types of consumers.<\/p>\n<p>Gold Bee has partnered with its local farmers as well as growers from Colorado to create their proprietary blend of high-CBD hemp flowers, resulting in clean and potent extracts that carry the full-spectrum of cannabinoids, terpenes, and other phytonutrients.<\/p>\n<p>The reason why I\u2019m putting this brand in the second place is that it doesn\u2019t offer such a broad potency range as Royal CBD. The maximum strength of the Gold Bee CBD oil is 1200 mg, so if your dose exceeds 30 mg daily, it may not offer the best value for the price. But if you benefit from lower dosages, this is definitely the best CBD oil you can find.<\/p>\n<p>Plus, the honey flavor tastes delicious.<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Pros<\/strong><\/td>\n<td><strong>Cons<\/strong><\/td>\n<\/tr>\n<tr>\n<td>\n<ul>\n<li>Sourced from US-grown organic hemp<\/li>\n<li>Contains full-spectrum CBD<\/li>\n<li>Up to 33 mg CBD\/mL<\/li>\n<li>Great potency range for beginners<\/li>\n<li>Third-party tested for potency and purity<\/li>\n<li>Great honey flavor<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li>No high-strength CBD oils<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><strong>3. CBDPure<\/strong><\/h3>\n<p><img class=\"aligncenter size-full wp-image-4017\" src=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/02\/cbd-pure-300-mg.jpg\" alt=\"cbd pure oil 300 mg\" width=\"350\" height=\"350\" srcset=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/02\/cbd-pure-300-mg.jpg 350w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/02\/cbd-pure-300-mg-300x300.jpg 300w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/02\/cbd-pure-300-mg-150x150.jpg 150w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/02\/cbd-pure-300-mg-100x100.jpg 100w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/><\/p>\n<h4><strong>Product Details<\/strong><\/h4>\n<table>\n<tbody>\n<tr>\n<td><strong>Potency<\/strong><\/td>\n<td>100 \u2013 1000 mg<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Flavors<\/strong><\/td>\n<td>None<\/td>\n<\/tr>\n<tr>\n<td><strong>CBD per serving<\/strong><\/td>\n<td>3.3 \u2013 33 mg\/mL<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4><strong>口交视频 CBDPure<\/strong><\/h4>\n<p>Looking for the best low-potency CBD oil on the market? Then CBDPure will be your best bet. This company covers the basic potency range for CBD extracts, offering 100 mg \u2013 1000 mg of CBD per bottle. The 1000 mg option has been recently added to CBDPure\u2019s lineup.<\/p>\n<p>Similar to other brands from this ranking, CBDPure uses organic hemp plants and makes its extracts with supercritical CO2, ensuring a high purity and potency of its products. This CBD oil contains the full-spectrum of non-psychoactive cannabinoids (with less than 0.3% THC), so you\u2019re getting the entourage effect from other hemp compounds. Full-spectrum extracts are believed to be more effective than isolates for symptoms like inflammation, anxiety, and convulsions.<\/p>\n<p>CBDPure is also one of the most transparent companies in the industry. The guys at CBDPure cover every detail of their activity, from farming to testing and packaging. They also have a 90-day return policy, which shows they\u2019re confident about the quality of their products. You can return the CBD oil for a full refund if you\u2019re not satisfied with the effects.<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Pros<\/strong><\/td>\n<td><strong>Cons<\/strong><\/td>\n<\/tr>\n<tr>\n<td>\n<ul>\n<li>Sourced from organic Colorado-grown hemp<\/li>\n<li>Extracted with supercritical CO2<\/li>\n<li>Lab-tested for potency and purity<\/li>\n<li>90-day return policy<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li>Only two forms of CBD available<\/li>\n<li>Low potency<\/li>\n<li>Premium pricing<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><strong>4. Hemp Bombs<\/strong><\/h3>\n<p><img class=\"aligncenter size-full wp-image-3701\" src=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/hemp-bomb-cbd-125.jpg\" alt=\"Hemp bomb cbd oil 125mg in a white background\" width=\"450\" height=\"450\" srcset=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/hemp-bomb-cbd-125.jpg 450w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/hemp-bomb-cbd-125-300x300.jpg 300w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/hemp-bomb-cbd-125-150x150.jpg 150w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/hemp-bomb-cbd-125-100x100.jpg 100w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\n<h4><strong>Product Details<\/strong><\/h4>\n<table>\n<tbody>\n<tr>\n<td><strong>Potency<\/strong><\/td>\n<td>125 \u2013 4000 mg<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Flavors<\/strong><\/td>\n<td>Natural, Acai Berry, Orange Creamsicle, Peppermint, Watermelon<\/td>\n<\/tr>\n<tr>\n<td><strong>CBD per serving<\/strong><\/td>\n<td>4 \u2013 133 mg\/mL<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4><strong>口交视频 Hemp Bombs<\/strong><\/h4>\n<p>Hemp Bombs is a US manufacturer that sells an extremely wide range of CBD-infused products. They offer both traditional formats like oil, capsules, and gummies, as well as less conventional products, such as beard oil and tattoo aftercare. Unlike other brands in this ranking, Hemp Bombs specializes in making isolate-based extracts. The company\u2019s products contain 99% pure CBD.<\/p>\n<p>Hemp Bombs CBD oil is a good option for people who need extremely high doses of CBD in their routine. At 4000 mg of CBD per bottle, it can get you supplied for months if you use it for preventive supplementation. However, keep in mind that this product doesn\u2019t contain other cannabinoids or terpenes from hemp, so you won\u2019t be getting the synergy from the entourage effect. This means that you may need to take more CBD as a result \u2014 and end up tired and sleepy.<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Pros<\/strong><\/td>\n<td><strong>Cons<\/strong><\/td>\n<\/tr>\n<tr>\n<td>\n<ul>\n<li>Sourced from organic hemp<\/li>\n<li>Extracted with CO2<\/li>\n<li>0% THC<\/li>\n<li>Available as broad-spectrum or isolate<\/li>\n<li>Third-party tested for CBD and contaminants<\/li>\n<li>Up to 4000 mg of CBD per bottle<\/li>\n<li>5 strengths to choose from<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li>Infused with synthetic flavorings<\/li>\n<li>No \u201centourage effect\u201d from other cannabinoids and terpenes<\/li>\n<li>Most people don\u2019t need such high doses of CBD oil in their routine<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><strong>5. CBDistillery<\/strong><\/h3>\n<h4><img class=\"aligncenter size-full wp-image-3695\" src=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/CBDistillery.jpg\" alt=\"CBDistillery CBD oil bottle in a white background\" width=\"450\" height=\"450\" srcset=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/CBDistillery.jpg 450w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/CBDistillery-300x300.jpg 300w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/CBDistillery-150x150.jpg 150w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/CBDistillery-100x100.jpg 100w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><strong>Product Details<\/strong><\/h4>\n<table>\n<tbody>\n<tr>\n<td><strong>Potency<\/strong><\/td>\n<td>250 \u2013 5000 mg<\/td>\n<\/tr>\n<tr>\n<td><strong>Available Flavors<\/strong><\/td>\n<td>None<\/td>\n<\/tr>\n<tr>\n<td><strong>Potency<\/strong><\/td>\n<td>8.3 \u2013 166 mg\/mL<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4><strong>口交视频 CBDistillery<\/strong><\/h4>\n<p>CBDistillery is one of the first companies to enter the U.S. CBD market, and one of the biggest brands in North America. This company offers full-spectrum CBD oil as well as broad-spectrum extracts. The latter products are labeled as \u201cpure oil,\u201d meaning they contain CBD and other cannabinoids but without traces of THC.<\/p>\n<p>CBDistillery caters to every type of CBD consumer, selling its oil in five different potencies \u2014 from 250 mg up to 5000 mg of total CBD. The only reason I\u2019m putting those guys in the last place here is their source of CBD. CBDistillery doesn\u2019t use organic hemp, but this is totally understandable considering the price of its products.<\/p>\n<p>My verdict? It\u2019s a great brand if you want high-quality CBD products in different forms for a wide range of symptoms \u2014 but without breaking the bank. For higher-end, organic products, I recommend the other manufacturers from our list.<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Pros<\/strong><\/td>\n<td><strong>Cons<\/strong><\/td>\n<\/tr>\n<tr>\n<td>\n<ul>\n<li>Available as full-spectrum or broad-spectrum CBD<\/li>\n<li>Extracted with CO2<\/li>\n<li>5 potency options to choose from<\/li>\n<li>Up to 166.6 mg of CBD per bottle<\/li>\n<li>Third-party tested for potency and purity<\/li>\n<li>Very affordable<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li>Made from non-organic hemp<\/li>\n<li>No flavored options<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><strong>What is CBD?<\/strong><\/h2>\n<p>CBD means <em>cannabidiol, <\/em>which is one of the two <a href=\"https:\/\/www.weednews.co\/what-is-cbd\/\" target=\"_blank\" rel=\"noopener noreferrer\">main cannabinoids found in cannabis plants<\/a> and used in medicine today. The other compound, tetrahydrocannabinol (THC) is the cannabinoid that gets people high due to its intoxicating properties. CBD doesn\u2019t have psychoactive effects like THC; in fact, it can alter the high caused by THC while providing a myriad of health benefits on its own.<\/p>\n<p>One of the greatest benefits of CBD is its impact on seizures and people who have epilepsy.<\/p>\n<p>Now, CBD can be extracted from marijuana and hemp, both of which belong to the <em>Cannabis sativa L. <\/em>family. Marijuana contains high levels of THC and its legal status is a bit hazy. On the federal level, marijuana is considered a Schedule 1 substance, meaning it\u2019s illegal and punishable with prison and hefty fines. Individual states can regulate marijuana on their own. So far, 11 states have legalized the recreational use of marijuana, while 37 states have a medical marijuana program.<\/p>\n<p>Hemp, on the other hand, contains only trace amounts of THC (0.3% or less). It has been grown historically for its fibers found in stalks and seeds. People have used hemp to make all kinds of items, from clothing to food to household items and ropes. Over the past few years, hemp flowers have become popular for CBD extraction.<\/p>\n<p>The 2018 Farm Bill legalized the <a href=\"https:\/\/www.weednews.co\/cbd-legal-status\/\" target=\"_blank\" rel=\"noopener noreferrer\">commercial use of hemp-derived CBD<\/a>. It also opened the doors for scientists to study the therapeutic potential of using CBD oil for epilepsy.<\/p>\n<p>In the next section, we\u2019ll discuss the relationship between epilepsy and the endocannabinoid system, the body\u2019s prime homeostatic network.<\/p>\n<h2><strong>What is Epilepsy?<\/strong><\/h2>\n<p><img class=\"wp-image-7501 size-full aligncenter\" src=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/03\/What_is_Seizure.jpg\" alt=\"Illustration of human brain having epilepsy on white background\" width=\"800\" height=\"450\" srcset=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/03\/What_is_Seizure.jpg 800w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/03\/What_is_Seizure-300x169.jpg 300w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/03\/What_is_Seizure-768x432.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p>As defined by the Epilepsy Foundation, epilepsy is a neurological condition characterized by unpredictable seizures. It\u2019s often referred to as \u201cseizure disorder\u201d and affects 25% of people with neurological disorders.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4561391\/\" target=\"_blank\" rel=\"noopener noreferrer\">Epilepsy is a spectrum disease<\/a>, meaning there\u2019s a wide range of types of seizures. It\u2019s also a chronic condition unlike isolated incidents such as seizures from alcohol withdrawal or extremely low blood sugar.<\/p>\n<p>People diagnosed with epilepsy are often unable to function normally during the day. Their safety becomes compromised because seizures can be triggered when a person is at work or driving a car. It can negatively impact relationships and create stigmas over patients.<\/p>\n<p>The public misunderstanding of the disorder, as well as the continuous failure of conventional treatments, are the two main problems for epilepsy patients.<\/p>\n<p>That\u2019s why so many people are turning to CBD oil to manage their seizures.<\/p>\n<h2><strong>CBD Oil for Seizures &amp; Epilepsy<\/strong><\/h2>\n<p>CBD has been demonstrated as a potent anti-seizure agent in many studies, although research in this field has been difficult to conduct given the federal regulations on cannabinoids.<\/p>\n<p>As mentioned, in December 2018 the government removed hemp and hemp-derived CBD from Schedule I of the Controlled Substances Act. Before that removal, human trials regarding the use of CBD for epilepsy were limited.<\/p>\n<p>Scientists are still trying to understand the exact mechanism behind the anti-seizure properties of CBD. One of the difficulties researchers encounter is that the effects of CBD vary between individuals. Also, many of the studies have been based on data pulled from uncontrolled environments.<\/p>\n<p>A 2017 study in The Journal of Epilepsy Research showed improvements in seizure control among patients with specific epilepsy disorders. However, researchers indicated that their study was inconclusive because they weren\u2019t able to decide if the reduction in seizures was a direct effect of CBD treatment.<\/p>\n<p>Interestingly, CBD has been proposed as a novel anti-inflammatory drug. Experts speculate that its anti-inflammatory effects can trigger an anticonvulsant mechanism that prevents seizures.<\/p>\n<p>The largest share of research in the subject of CBD and seizures comes from studies conducted on its synthetic counterpart H2CBD. This form of CBD showed an effective reduction of seizures in rats. The results of this study opened the way for further research on CBD because its synthetic equivalents aren\u2019t as strictly regulated; they\u2019re less liable to violate state and federal regulations.<\/p>\n<h2><strong>Epidiolex: The First CBD-based Drug for Epilepsy Approved by the FDA<\/strong><\/h2>\n<p><img class=\"aligncenter size-full wp-image-3731\" src=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/Epidiolex_RGB_Sch_v01.jpg\" alt=\"Epidiolex logo in a white background\" width=\"800\" height=\"239\" srcset=\"https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/Epidiolex_RGB_Sch_v01.jpg 800w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/Epidiolex_RGB_Sch_v01-300x90.jpg 300w, https:\/\/www.weednews.co\/wp-content\/uploads\/2020\/01\/Epidiolex_RGB_Sch_v01-768x229.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p>Epidiolex is the first CBD-based medication that passed clinical trials in the USA and has been <a href=\"https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms\" target=\"_blank\" rel=\"noopener noreferrer\">accepted by the Food and Drug Administration<\/a> (FDA). Let\u2019s take a closer look at this drug and the research on its anticonvulsant effects.<\/p>\n<h3><strong>What is Epidiolex?<\/strong><\/h3>\n<p>Epidiolex is an anti-seizure medication composed of CBD extract \u2014 the oil is 98% pure. Such a high level of purity ensures a consistent, potent dose of CBD for its users. Unlike hemp-derived CBD oil, Epidiolex doesn\u2019t contain any other cannabinoids and terpenes.<\/p>\n<h3><strong>The Clinical Trials<\/strong><\/h3>\n<p>Epidiolex was the first CBD-based drug tested in controlled clinical trials, meaning that it involved two groups of patients. The control group was treated with a placebo, while the other one took a dose of CBD for their seizures. On top of this, the trials were double-blind and randomized, so researchers didn\u2019t have any information about who was in the CBD group and who was receiving the placebo.<\/p>\n<p>The Epidiolex studies targeted the treatment of two major types of epilepsy: Dravet syndrome and Lennox-Gastaut syndrome, both of which are prevalent in children.<\/p>\n<h3><strong>The Findings<\/strong><\/h3>\n<p>The study involved almost 1,000 participants. Every subject in the trial was taking other anti-seizure medications besides CBD. Those who took Epidiolex were divided into different groups based on their CBD dosage.<\/p>\n<p>On top of the positive effects, some of the participants reported several adverse reactions, such as:<\/p>\n<ul>\n<li>Changes in appetite<\/li>\n<li>Lethargy<\/li>\n<li>Diarrhea<\/li>\n<li>Insomnia<\/li>\n<li>Rash<\/li>\n<li><a href=\"https:\/\/www.weednews.co\/best-cbd-oil-for-sleep\/\" target=\"_blank\" rel=\"noopener noreferrer\">Sleepiness<\/a><\/li>\n<li>Fatigue<\/li>\n<\/ul>\n<p>These side effects were more common in those who took a higher dose of CBD. Scientists also noted that it wasn\u2019t clear if the side effects resulted from CBD or due to the prescribed anti-seizure medications that the subjects were already taking, or the interaction between the two.<\/p>\n<p>For the study on Lennox Gastaut Syndrome, CBD combined with traditional anti-seizure drugs caused a significant drop in the frequency and severity of seizures in both children and adults.<\/p>\n<p>In the study testing, the efficacy of CBD for Dravet syndrome seizures caused a more significant decrease in convulsive seizures compared to the control group. However, those taking CBD also showed more side effects.<\/p>\n<h3><strong>Summary and Discussion of the Trials<\/strong><\/h3>\n<p>In the summary of the Epidiolex trials, scientists concluded that the effects of CBD show great promise for the reduction of seizures through controlled treatment.<\/p>\n<p>However, the studies also found a few limitations. For one, they only analyzed two types of epilepsy: Dravet syndrome and Lennox Gastaut syndrome. As mentioned above, the government has only recently given the green light for such studies, so we need some time to draw more conclusions from studies on other types of epilepsy.<\/p>\n<p>The good news is that these trials are inevitable.<\/p>\n<p>There are also ongoing trials investigating how Epidiolex affects people with other types of seizure disorders. For example, the Epilepsy Foundation lists several active studies that are testing the efficacy of CBD on Tuberous Sclerosis Complex and Sturge-Weber Syndrome.<\/p>\n<p>Another problem that needs to be resolved is the cause of the aforementioned side effects. Is it the CBD? Or are these adverse reactions triggered by traditional meds? CBD is known for interacting with many prescription medications, so potential drug interactions may hold the answer to that question.<\/p>\n<h2><strong>Anecdotes from Epilepsy Patients<\/strong><\/h2>\n<p>Despite some obvious limits in research, it\u2019s easy to find stories of patients giving testimonies about the efficacy of CBD oil in treating their seizures. You can search parenting groups on Facebook because a large portion of anecdotal evidence comes from parents with epileptic children. While these stories aren\u2019t backed by scientific research, they do show that CBD has helped many people deal with their seizures.<\/p>\n<h2><strong>Key Takeaways on CBD and Seizures<\/strong><\/h2>\n<p>As we have seen, there\u2019s a lot to learn when it comes to using CBD for epilepsy. Scientists are still unsure how CBD helps individuals in the management of their seizures, but one thing is certain \u2014 CBD can significantly improve the quality of life of those diagnosed with epilepsy.<\/p>\n<p>As with anything that affects the human brain, the impact of CBD on epilepsy is a very complex subject. Until the federal government loosens its policies surrounding cannabis-derived CBD, it may be difficult to carry out clinical trials on CBD oil.<\/p>\n<p>While limited in their scope, studies on drugs like Epidiolex show promising results for epilepsy patients. The research combined with anecdotal evidence from families all across the world provides hope that we will finally understand the mechanism behind the anticonvulsant effects of CBD oil.<\/p>\n<p>As with every health supplement, quality is paramount if you want to fully experience the benefits of CBD on your health. Make sure you always purchase your <a href=\"https:\/\/www.weednews.co\/where-to-buy-cbd-products\/\" target=\"_blank\" rel=\"noopener noreferrer\">CBD oil from a trusted source<\/a>. You can do your own research or use our recommendations to find premium-quality products at a decent price.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>June 25, 2018, was a historic moment for cannabis. On that day, the FDA approved the first CBD-based drug Epidiolex. Before making it to the market in the US, Epidiolex has been tested in many clinical studies around the world regarding the use of cannabis as a treatment for epilepsy. The fact Epidiolex was approved [&hellip;]<\/p>\n","protected":false},"author":175,"featured_media":7868,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[374],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v15.1.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>5 Best CBD Oils to Reduce Seizures and Help With Epilepsy in 2022<\/title>\n<meta name=\"description\" content=\"How does CBD oil help with seizures and epilepsy? What brands sell the best CBD products in 2022? 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